Acetadote vs. its authorized generic and generics

Acetadote is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How to pay the least

Given by your care team

Billed by the clinic

Acetadote is given by a doctor or nurse, not picked up at a pharmacy.

Ask your care team or your plan what you’d pay before your visit.

Compare every option

Brand nameAcetadote

Authorized genericacetylcysteine

Regular genericacetylcysteine

What you’d pay

Cash priceAsk the pharmacyUsually the highest price

Cash priceAsk the pharmacyOften less than Acetadote

Cash priceAsk the pharmacyUsually the lowest

Same as Acetadote?

The original

Same medicine

Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Acetadote’s maker. Ask the pharmacy for Acetadote’s cash price. With insurance, ask what your plan charges.

Authorized genericThe NDC to ask for

The same medicine as Acetadote, without the brand name. Give the pharmacy its NDC to get it.

acetylcysteine

Sold by

Padagis

Given by your care team

This is given by IV in the hospital, not picked up at a pharmacy.

NDC (for your care team)

200 mg/mLinjection
- 0574-0805-3011-digit: 00574-0805-304 vials, 30 mL each

Source: FDA, updated October 30, 2026

What to ask your care team

“Which version of Acetadote do you use: the brand, the authorized generic or a regular generic? What would I pay for each?”

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

Acetadote doesn’t come in this strength, so there’s no brand label to compare.

Authorized generic package label from Padagis — Authorized genericPadagis

See the ingredients

Active: acetylcysteine 200 mg/mL

Inactive:

Sodium hydroxide
Water

Regular genericWho makes it

7 companies sell an FDA-rated generic of Acetadote. It’s given by your care team, who choose which one to use.

Eugia6 g/30 mL

Product page on eugiaus.com

How it looks, what’s in it, NDCs

6 g/30 mL

Package NDC
Carton of 120 mL 55150-259-30

Inactive ingredients: edetate disodium, sodium hydroxide, water
FDA label
Fresenius Kabi200 mg/mL

How it looks, what’s in it, NDCs

200 mg/mL

Package NDC
Carton of 120 mL 63323-963-44

200 mg/mL

Package NDC
Carton of 120 mL 63323-963-30

Inactive ingredients: edetate disodium, sodium hydroxide, water
FDA label
Glenmark Pharmaceuticals200 mg/mL

Product page on glenmarkpharma-us.com

How it looks, what’s in it, NDCs

200 mg/mL

Package NDC
Carton of 120 mL 68462-946-12

Inactive ingredients: water, sodium hydroxide, edetate disodium
FDA label
Hikma Pharmaceuticals200 mg/mL

Made by Onesource Specialty Pharma

Packages and NDCs

200 mg/mL

Package NDC
Carton of 120 mL 0143-9433-04

FDA label
Sagent Pharmaceuticals200 mg/mL

Product page on sagentpharma.com

How it looks, what’s in it, NDCs

200 mg/mL

Package NDC
Carton of 120 mL 25021-812-66

200 mg/mL

Package NDC
Carton of 120 mL 25021-812-30

Inactive ingredients: edetate disodium, sodium hydroxide, water
FDA label
Somerset Therapeutics200 mg/mL

Product page on somersetpharma.com

How it looks, what’s in it, NDCs

200 mg/mL

Package NDC
Carton of 120 mL 70069-788-04

Inactive ingredients: nitrogen, sodium hydroxide, water
FDA label
Xellia Pharmaceuticals200 mg/mL

Made by Onesource Specialty Pharma

Packages and NDCs

200 mg/mL

Package NDC
Carton of 120 mL 70594-111-02

FDA label

Package	NDC
Carton of 120 mL	55150-259-30

Package	NDC
Carton of 120 mL	63323-963-44

Package	NDC
Carton of 120 mL	63323-963-30

Package	NDC
Carton of 120 mL	68462-946-12

Package	NDC
Carton of 120 mL	0143-9433-04

Package	NDC
Carton of 120 mL	25021-812-66

Package	NDC
Carton of 120 mL	25021-812-30

Package	NDC
Carton of 120 mL	70069-788-04

Package	NDC
Carton of 120 mL	70594-111-02

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

Preventing liver damage after an acetaminophen overdose

What the FDA label says

ACETADOTE is an antidote for acetaminophen overdose indicated to prevent or lessen hepatic injury after ingestion of a potentially hepatotoxic quantity of acetaminophen in adults and pediatric patients who weigh 5 kg or greater with acute ingestion or from repeated supratherapeutic ingestion (RSI).

Source: the FDA label for Acetadote (Cumberland Pharmaceuticals Inc.), April 30, 2025. Full label on DailyMed

Good to know

It may look different from Acetadote (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Coverage depends on your plan. Your care team or insurer can tell you what you’d pay.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/acetadote/