How do you pay?

How to pay the least

From

$22.88 for 30 tablets delivered ($17.63 plus $5.25 shipping)

Generic doxycycline hyclate from Cost Plus Drugs, by mail. Pick the strength on your label above for its own price.

  1. Make a free account on costplusdrugs.com. Ask your prescriber to send the prescription there, or Cost Plus Drugs can transfer it.Open Cost Plus Drugs 
  2. Order generic doxycycline hyclate. It comes by mail.

A regular generic has the same active ingredient as Acticlate, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameActiclate
Authorized genericdoxycycline hyclate
Regular genericdoxycycline hyclate
What you’d pay
Not soldNo longer sold
Cash priceAsk the pharmacyUsually among the lowest
From$22.88for 30 tablets at Cost Plus Drugs, with shipping
Same as Acticlate?
–
Same medicine
Same active ingredientFillers and dyes can differ

Brand nameNot sold

Acticlate itself isn’t sold as a prescription anymore. Its generic versions, if any, are in the other tabs.

See the authorized generic →

Authorized genericThe NDC to ask for

The same medicine as Acticlate, without the brand name. Give the pharmacy its NDC to get it.

doxycycline hyclate

Sold by
  • Chartwell RXThe company behind Acticlate
Your strength
NDC to ask for
  • 75 mgtablet
    • 62135-907-2011-digit: 62135-0907-2020 tablets per bottle
  • 150 mgtablet
    • 62135-908-2011-digit: 62135-0908-2020 tablets per bottle

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Acticlate, can you tell me what I’d pay for the brand, for the authorized generic from Chartwell RX, and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

75 mg tablet

Acticlate itself isn’t sold anymore, so there’s no current brand label to compare. Here’s the authorized generic’s label.

Authorized genericChartwell RX
See the ingredients

Active: doxycycline hyclate 75 mg

Inactive:

  • Croscarmellose sodium
  • FD&C Blue No. 2
  • Magnesium stearate
  • Microcrystalline cellulose
  • Polyethylene glycol 8000
  • Polyvinyl alcohol
  • Sodium lauryl sulfate
  • Talc
  • Titanium dioxide

150 mg tablet

Acticlate itself isn’t sold anymore, so there’s no current brand label to compare. Here’s the authorized generic’s label.

Authorized genericChartwell RX
See the ingredients

Active: doxycycline hyclate 150 mg

Inactive:

  • Croscarmellose sodium
  • FD&C Blue No. 2
  • Ferric oxide yellow
  • Magnesium stearate
  • Microcrystalline cellulose
  • Polyethylene glycol 8000
  • Polyvinyl alcohol
  • Sodium lauryl sulfate
  • Talc
  • Titanium dioxide

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic doxycycline hyclate, lowest first.

Delivered

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericWho makes it

3 companies sell a generic of Acticlate that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • Ajanta PharmaAll 2 strengths

    Has dyes: FD&C Blue No. 2, FD&C Yellow No. 6

    Product page on ajantapharmausa.com

    How it looks, what’s in it, NDCs

    75 mg Blue, round, 8 mm, marked “DY / 2”

    PackageNDC
    Bottle of 6027241-153-02

    150 mg Yellowish-green, capsule, 16 mm, marked “D / Y / 1”

    PackageNDC
    Bottle of 6027241-154-02

    Inactive ingredients: microcrystalline cellulose, sodium lauryl sulfate, magnesium stearate, hypromellose, titanium dioxide, polyethylene glycol, FD&C Blue No. 2, FD&C Yellow No. 6, ferric oxide yellow

    FDA label

  • Alembic PharmaceuticalsAll 2 strengths

    Has dyes: FD&C Blue No. 1, FD&C Blue No. 2

    How it looks, what’s in it, NDCs

    75 mg Teal, round, 8 mm, marked “L22”

    PackageNDC
    Bottle of 6062332-387-60
    Bottle of 100062332-387-91

    150 mg Mossy-green, oval, 16 mm, marked “L / 2 / 3”

    PackageNDC
    Bottle of 6062332-388-60
    Bottle of 100062332-388-91

    Inactive ingredients: microcrystalline cellulose, sodium lauryl sulfate, croscarmellose sodium, magnesium stearate, polyvinyl alcohol, titanium dioxide, polyethylene glycol 3350, talc, ferric oxide yellow, FD&C Blue No. 1, FD&C Blue No. 2

    FDA label

  • Lupin PharmaceuticalsAll 2 strengths

    Has dyes: FD&C Blue No. 1, FD&C Yellow No. 6, FD&C Blue No. 2

    How it looks, what’s in it, NDCs

    75 mg Light-teal, round, 9 mm, marked “LU / C80”

    PackageNDC
    Bottle of 6068180-653-07

    150 mg Mossy-green, oval, 16 mm, marked “C / C / C”

    PackageNDC
    Bottle of 6068180-654-07

    Inactive ingredients: cellulose, microcrystalline, croscarmellose sodium, FD&C Blue No. 1, FD&C Yellow No. 6, hypromellose 2910 (5 mpa.s), magnesium stearate, polyethylene glycol 3350, polyvinyl alcohol, sodium lauryl sulfate, talc, titanium dioxide, FD&C Blue No. 2, ferric oxide yellow

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

What the FDA label says

Doxycycline hyclate tablets and doxycycline hyclate capsules are tetracycline class drugs indicated for:

  • Rickettsial infections
  • Sexually transmitted infections
  • Respiratory tract infections
  • Specific bacterial infections
  • Ophthalmic infections
  • Anthrax, including inhalational anthrax (post-exposure)
  • Alternative treatment for selected infections when penicillin is contraindicated
  • Adjunctive therapy for acute intestinal amebiasis and severe acne
  • Prophylaxis of malaria

To reduce the development of drug-resistant bacteria and maintain the effectiveness of doxycycline hyclate and other antibacterial drugs, doxycycline hyclate should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

Source: the FDA label for Doxycycline Hyclate (Chartwell RX, LLC), June 30, 2026. Full label on DailyMed 

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