Advair HFA vs. its authorized generic and generics

How to pay the least

Lowest posted price

$35 or less a month

Advair HFA from GSK, without insurance.

Ask about the authorized generic Advair HFA itself, without the brand name. Ask your pharmacy for its price; its NDC is on this page.

See its NDC

Sold only in a different form, strength or formula. Switching to one would need a new prescription, so ask your prescriber whether it could work for you.

Compare every option

Brand nameAdvair HFA

Authorized genericfluticasone and salmeterol xinafoate

Regular genericfluticasone and salmeterol xinafoate

What you’d pay

Cash price$35or less a month with the maker’s card

Cash priceAsk the pharmacyUsually the lowest

Other forms onlyAsk your doctor

Same as Advair HFA?

The original

Same medicine

–

Brand nameThe maker’s card

Advair HFA’s maker has a savings card that lowers what you pay at the pharmacy.

GSK Pay No More Than $35 Coupon

Savings card from GSK

No insurance $35 or less a month

Insurance $35 or less a month

In the maker’s words

“Eligible patients will pay no more than $35 per month for their ADVAIR prescription.”

From the maker’s offer on advair.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericThe NDC to ask for

The same medicine as Advair HFA, without the brand name. Give the pharmacy its NDC to get it.

fluticasone and salmeterol xinafoate

Sold by

Prasco LaboratoriesMade by GlaxoSmithKline, the company behind Advair HFA

Your strength

NDC to ask for

45 mcg / 21 mcginhaler
- 66993-086-9611-digit: 66993-0086-96120 puffs per inhaler
115 mcg / 21 mcginhaler
- 66993-087-9611-digit: 66993-0087-96120 puffs per inhaler
230 mcg / 21 mcginhaler
- 66993-088-9611-digit: 66993-0088-96120 puffs per inhaler

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Advair HFA, can you tell me what I’d pay for the brand, for the authorized generic from Prasco Laboratories?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

45 mcg / 21 mcg inhaler

Same active and inactive ingredients as Advair HFA.

Advair HFA package label — BrandAdvair HFA

Authorized generic package label from Prasco Laboratories — Authorized genericPrasco Laboratories

See the ingredients

Active: fluticasone propionate 45 mcg · salmeterol xinafoate 21 mcg

Inactive, on both labels:

Norflurane

115 mcg / 21 mcg inhaler

Same active and inactive ingredients as Advair HFA.

See the ingredients

Active: fluticasone propionate 115 mcg · salmeterol xinafoate 21 mcg

Inactive, on both labels:

Norflurane

230 mcg / 21 mcg inhaler

Same active and inactive ingredients as Advair HFA.

See the ingredients

Active: fluticasone propionate 230 mcg · salmeterol xinafoate 21 mcg

Inactive, on both labels:

Norflurane

Regular genericNot sold

Sold only in a different form, strength or formula. Switching to one would need a new prescription, so ask your prescriber whether it could work for you. Generics usually come once the brand’s patents and exclusivity end. Until then, the authorized generic is the lower-cost way to get Advair HFA.

See the authorized generic →

What it’s used for

Asthma

What the FDA label says

ADVAIR HFA is a combination of fluticasone propionate, an inhaled corticosteroid, and salmeterol, a long-acting beta2‑adrenergic agonist (LABA), indicated for treatment of asthma in adult and adolescent patients aged 12 years and older.

Limitations of use: Not indicated for relief of acute bronchospasm.

Source: the FDA label for Advair HFA (GlaxoSmithKline LLC), May 23, 2024. Full label on DailyMed

Good to know

It may look different from Advair HFA (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Cash prices can differ a lot from one pharmacy to the next, so it can pay to ask two. With insurance, what you pay depends on your plan.
If your pharmacy doesn’t stock it, they can often order it within a day or two.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/advair-hfa/