Afrezza is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.
Compare every option
Question
Brand nameAfrezza
Authorized genericinsulin human
Regular genericinsulin human
What you’d pay
Cash price$99a box with the maker’s card
Not soldThere isn’t one
Not soldNone sold yet
Same as Afrezza?
The original
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Coverage: With Medicare, a month’s supply of a covered insulin costs no more than $35.
“Pay as little as $35 PER MONTH with the Afrezza Savings Card…”
“Cash pay program $99/box. Void where prohibited.”
From the maker’s offer on afrezza.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Maker’s card or discount card?
A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s price above. You can usually use one or the other on a fill, not both.
Brand nameWith a free discount coupon
Optum Perks, Optum’s free discount coupon, lists these prices for Afrezza without insurance. Show the coupon from its page at the pharmacy; it can’t be used with insurance.
From Optum Perks, read November 2, 2026, with no location set. Its page opens on this dose; other doses and pharmacies near you are priced there too. With insurance, check your co-pay first: it may be lower.
Authorized genericNot sold
There isn’t one. An authorized generic is Afrezza itself, from the same company, sold without the brand name, and usually for less. For now Afrezza is the only choice; its maker’s savings card can lower what you pay.
Afrezza is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.
AFREZZA ® is a rapid acting inhaled human insulin indicated to improve glycemic control in adult and pediatric patients 6 years of age and older with diabetes mellitus.
Limitations of Use:
Not recommended for the treatment of diabetic ketoacidosis (DKA)
Not recommended in patients who smoke or who have recently stopped smoking
Source: the FDA label for Afrezza (Mannkind Corporation), May 30, 2026. Full label on DailyMed
Good to know
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.
Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/afrezza/