AlphaNine SD savings card: as little as $0 with commercial insurance

AlphaNine SD is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How to pay the least

Given by your care team

Billed by the clinic

AlphaNine SD is given by a doctor or nurse, not picked up at a pharmacy.

Ask your care team or your plan what you’d pay before your visit.

Compare every option

Brand nameAlphaNine SD

Authorized genericcoagulation factor ix (human)

Regular genericcoagulation factor ix (human)

What you’d pay

Cash priceAsk the pharmacy

Not soldThere isn’t one

Not soldAsk the pharmacy

Same as AlphaNine SD?

The original

–

Brand nameThe maker’s card

Factors for Health $0 Copay Assistance Program

Savings card from Grifols

No insuranceNeeds insuranceNo cash price listed.

Insurance · as little as $0

In the maker’s words

“The $0 Copay Assistance Program, which may cover out-of-pocket expenses not covered or partially covered by insurance, with no annual limits…”

From the maker’s offer on alphaninesd.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericNot sold

There isn’t one. An authorized generic is AlphaNine SD itself, from the same company, sold without the brand name, and usually for less. For now AlphaNine SD is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

AlphaNine SD is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

Treating and preventing bleeding in hemophilia B

What the FDA label says

AlphaNine SD is indicated for the prevention and control of bleeding in patients with Factor IX deficiency due to hemophilia B. AlphaNine SD contains low, non-therapeutic levels of Factors II, VII, and X, and, therefore, is not indicated for the treatment of Factor II, VII or X deficiencies. This product is also not indicated for the reversal of coumarin anticoagulant-induced hemorrhage, nor in the treatment of hemophilia A patients with inhibitors to Factor VIII.

Source: the FDA label for AlphaNine SD (GRIFOLS USA, LLC), May 27, 2025. Full label on DailyMed

Good to know

“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to the clinic’s billing office.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/alphanine-sd/