How do you pay?

How to pay the least

Ask for the cash price

Amphadase

Amphadase is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

  1. Ask your pharmacy for Amphadase’s cash price, and one or two other pharmacies too.

Compare every option

Question
Brand nameAmphadase
Authorized generichyaluronidase
Regular generichyaluronidase
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldAsk the pharmacy
Same as Amphadase?
The original
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Brand nameWith a free discount coupon

Optum Perks, Optum’s free discount coupon, lists these prices for Amphadase without insurance. Show the coupon from its page at the pharmacy; it can’t be used with insurance.

From Optum Perks, read November 2, 2026, with no location set. Its page opens on this dose; other doses and pharmacies near you are priced there too. With insurance, check your co-pay first: it may be lower.

Authorized genericNot sold

There isn’t one. An authorized generic is Amphadase itself, from the same company, sold without the brand name, and usually for less. For now Amphadase is the only choice; ask the pharmacy for its cash price, or your plan what it charges.

See the brand name →

Regular genericNot sold

Amphadase is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, ask the pharmacy for Amphadase’s cash price, or your plan what it charges.

See the brand name →

What it’s used for

What the FDA label says

Amphadase® is an endoglycosidase indicated as an adjuvant: • in subcutaneous fluid administration for achieving hydration • to increase absorption and dispersion of other injected drugs • in subcutaneous urography for improving resorption of radiopaque agents

Source: the FDA label for Amphadase (Amphastar Pharmaceuticals, Inc.), February 1, 2024. Full label on DailyMed 

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