How do you pay?

How to pay the least

Lowest price

$15.98 for 30 tablets delivered ($10.73 plus $5.25 shipping)

Generic dalfampridine ER 10 mg from Cost Plus Drugs, by mail

  1. Make a free account on costplusdrugs.com. Ask your prescriber to send the prescription there, or Cost Plus Drugs can transfer it.Open Cost Plus Drugs 
  2. Order generic dalfampridine ER 10 mg. It comes by mail.

A regular generic has the same active ingredient as Ampyra, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameAmpyra
Authorized genericdalfampridine
Regular genericdalfampridine
What you’d pay
Cash priceAsk the pharmacyUsually the highest price
Not soldNo longer sold
Lowest$15.98for 30 tablets at Cost Plus Drugs, with shipping
Same as Ampyra?
The original
–
Same active ingredientFillers and dyes can differ

Brand nameThe maker’s card

Ampyra’s maker has a savings card that lowers what you pay at the pharmacy.

MyAmpyra Co-Pay Program

Savings card from Merz Pharmaceuticals

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a prescription

Sign up on ampyra.com 

Or call 1-855-866-9255.

In the maker’s words

“Eligible commercially insured patients may receive AMPYRA for as little as $0.”

From the maker’s offer on ampyra.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericNot sold now

An authorized generic of Ampyra was sold before, but it isn’t sold now. Ask your pharmacist whether a regular generic (dalfampridine) is available.

Source: FDA, updated October 30, 2026

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic dalfampridine, lowest first.

Pick up in storeDelivered

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericMakers and their savings programs

5 companies sell a generic of Ampyra that the FDA rates a substitute. A pharmacy fills whichever one it stocks. One of them has its own savings program, listed first. It works only with that maker’s version. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • CivicaScript10 mg

    Made by Alkem Laboratories

    MaxRP (maximum recommended price to the consumer)

    “CivicaScript’s MaxRP® policy is our maximum recommended price to the consumer.” (anyone)

    See the program

    Product page on civicascript.com

    How it looks, what’s in it, NDCs

    10 mg White to off white, oval, 13 mm, marked “D / 10”

    PackageNDC
    Bottle of 6082249-702-60

    Inactive ingredients: silicon dioxide, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, titanium dioxide

    FDA label

  • Accord Healthcare10 mg

    Product page on accordhealthcare.us

    How it looks, what’s in it, NDCs

    10 mg White to off white, oval, 13 mm, marked “FH6”

    PackageNDC
    Bottle of 6016729-292-12

    Inactive ingredients: hypromellose 2208 (100 mpa.s), hypromellose 2910 (6 mpa.s), cellulose, microcrystalline, silicon dioxide, magnesium stearate, titanium dioxide, polyethylene glycol 400

    FDA label

  • Actavis Pharma10 mg
    How it looks, what’s in it, NDCs

    10 mg White to off-white, oval, 13 mm, marked “WPI / 2533”

    PackageNDC
    Bottle of 600591-2533-60

    Inactive ingredients: silicon dioxide, anhydrous dibasic calcium phosphate, hypromellose, magnesium stearate, polyethylene glycol, titanium dioxide

  • Ascend Laboratories10 mg

    Made by Alkem Laboratories

    How it looks, what’s in it, NDCs

    10 mg White to off white, oval, 13 mm, marked “D / 10”

    PackageNDC
    Bottle of 6067877-444-60
    Bottle of 9067877-444-90
    Bottle of 50067877-444-05

    Inactive ingredients: silicon dioxide, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, titanium dioxide

    FDA label

  • Micro Labs10 mg

    Product page on microlabsusa.com

    How it looks, what’s in it, NDCs

    10 mg White to-off whie, oval, 13 mm, marked “C51”

    PackageNDC
    Bottle of 6042571-275-60
    Bottle of 50042571-275-05
    Bottle of 100042571-275-10

    Inactive ingredients: hypromelloses, magnesium stearate, microcrystalline cellulose, polyethylene glycol, silicon dioxide, titanium dioxide

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

What the FDA label says

AMPYRA ® (dalfampridine) is a potassium channel blocker indicated to improve walking in adult patients with multiple sclerosis (MS). This was demonstrated by an increase in walking speed.

Source: the FDA label for Ampyra (Merz Pharmaceuticals, LLC), January 16, 2026. Full label on DailyMed