Amvuttra savings card: $0 a dose with commercial insurance

How to pay the least

Ask for the cash price

Amvuttra

We didn’t find one.

Ask your pharmacy for Amvuttra’s cash price, and one or two other pharmacies too.
Amvuttra’s savings card works only with insurance from a job or one you bought.

Compare every option

Brand nameAmvuttra

Authorized genericvutrisiran

Regular genericvutrisiran

What you’d pay

Cash priceAsk the pharmacy

Not soldThere isn’t one

Not soldNone found

Same as Amvuttra?

The original

–

Brand nameThe maker’s card

Alnylam Assist Copay Program

Savings card from Alnylam Pharmaceuticals

No insuranceNeeds insuranceNo cash price listed.

Insurance $0 a dose

Or call 1-833-256-2748.

In the maker’s words

“Most patients treated with AMVUTTRA pay $0 out-of-pocket.”

From the maker’s offer on amvuttra.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Amvuttra itself, from the same company, sold without the brand name, and usually for less. For now Amvuttra is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

We didn’t find one. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

AMVUTTRA is a transthyretin-directed small interfering RNA indicated for the treatment of:

the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults
the cardiomyopathy of wild-type or hereditary transthyretin-mediated amyloidosis in adults to reduce cardiovascular mortality, cardiovascular hospitalizations and urgent heart failure visits

Source: the FDA label for Amvuttra (Alnylam Pharmaceuticals, Inc.), November 6, 2025. Full label on DailyMed

Good to know

“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/amvuttra/