Aplenzin vs. its authorized generic and generics

How to pay the least

Ask for the cash price

Authorized generic

Aplenzin itself, without the brand name. It usually costs less than Aplenzin.

Ask your pharmacy for the cash price of Aplenzin’s authorized generic. Its NDC is on this page; the pharmacy may need to order it.See its NDC
Ask for Aplenzin’s cash price too, and pick the lower one.

Free from the maker, if you qualify Bausch Health Patient Assistance Program. Your total annual household income must not exceed 300% of the Federal Poverty Level (FPL) based on household size Or call 1-833-862-8727.

See if you qualify

Sold only in a different form, strength or formula. Switching to one would need a new prescription, so ask your prescriber whether it could work for you.

Compare every option

Brand nameAplenzin

Authorized genericbupropion

Regular genericbupropion

What you’d pay

Cash priceAsk the pharmacyUsually the highest price

Cash priceAsk the pharmacyOften less than Aplenzin

Other forms onlyAsk your doctor

Same as Aplenzin?

The original

Same medicine

–

Brand nameThe maker’s card

Aplenzin’s maker has a savings card that lowers what you pay at the pharmacy.

APLENZIN Copay Savings Card

Savings card from Bausch Health

No insuranceNeeds insuranceNo cash price listed.

Insurance · as little as $0 a fill

Or call 1-855-300-1714. See the offer on aplenzin.com

In the maker’s words

“Eligible patients may pay as little as $0 for APLENZIN…”

From the maker’s offer on aplenzin.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericThe NDC to ask for

The same medicine as Aplenzin, without the brand name. Give the pharmacy its NDC to get it.

bupropion

Sold by

Oceanside PharmaceuticalsPart of Bausch Health, the company behind Aplenzin

Your strength

NDC to ask for

174 mgextended-release tablet
- 68682-580-3011-digit: 68682-0580-3030 tablets per bottle
348 mgextended-release tablet
- 68682-581-3011-digit: 68682-0581-3030 tablets per bottle
522 mgextended-release tablet
- 68682-582-3011-digit: 68682-0582-3030 tablets per bottle

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Aplenzin, can you tell me what I’d pay for the brand, for the authorized generic from Oceanside Pharmaceuticals?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

174 mg extended-release tablet

Same active and inactive ingredients as Aplenzin.

Authorized generic package label from Oceanside Pharmaceuticals — Authorized genericOceanside Pharmaceuticals

See the ingredients

Active: bupropion hydrobromide 174 mg

Inactive, on both labels:

Carnauba wax
Crospovidone
Dibutyl sebacate
Ethylcellulose
Glyceryl dibehenate
Polyethylene glycol
Polyvinyl alcohol

348 mg extended-release tablet

Same active and inactive ingredients as Aplenzin.

See the ingredients

Active: bupropion hydrobromide 348 mg

Inactive, on both labels:

Carnauba wax
Crospovidone
Dibutyl sebacate
Ethylcellulose
Glyceryl dibehenate
Polyethylene glycol
Polyvinyl alcohol

522 mg extended-release tablet

Same active and inactive ingredients as Aplenzin.

See the ingredients

Active: bupropion hydrobromide 522 mg

Inactive, on both labels:

Crospovidone
Dibutyl sebacate
Ethylcellulose
Glyceryl dibehenate
Polyethylene glycol
Polyvinyl alcohol

Regular genericNot sold

Sold only in a different form, strength or formula. Switching to one would need a new prescription, so ask your prescriber whether it could work for you. Generics usually come once the brand’s patents and exclusivity end. Until then, the authorized generic is the lower-cost way to get Aplenzin.

See the authorized generic →

What it’s used for

What the FDA label says

APLENZIN is an aminoketone antidepressant, indicated for the treatment of major depressive disorder (MDD) and seasonal affective disorder (SAD). Periodically reevaluate long-term usefulness for the individual patient.

Source: the FDA label for Aplenzin (Bausch Health US, LLC), March 4, 2026. Full label on DailyMed

Good to know

It may look different from Aplenzin (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Cash prices can differ a lot from one pharmacy to the next, so it can pay to ask two. With insurance, what you pay depends on your plan.
If your pharmacy doesn’t stock it, they can often order it within a day or two.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/aplenzin/