How do you pay?

How to pay the least

Lowest price

$15.29 for 30 capsules delivered ($10.04 plus $5.25 shipping)

Generic mesalamine ER 375 mg from Cost Plus Drugs, by mail

  1. Make a free account on costplusdrugs.com. Ask your prescriber to send the prescription there, or Cost Plus Drugs can transfer it.Open Cost Plus Drugs 
  2. Order generic mesalamine ER 375 mg. It comes by mail.

A regular generic has the same active ingredient as Apriso, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameApriso
Authorized genericmesalamine
Regular genericmesalamine
What you’d pay
Cash priceAsk the pharmacyUsually the highest price
Cash priceAsk the pharmacyUsually among the lowest
Cash price$15.29for 30 capsules at Cost Plus Drugs, with shipping
Same as Apriso?
The original
Same medicine
Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Apriso’s maker. Ask the pharmacy for Apriso’s cash price. With insurance, ask what your plan charges.

Authorized genericThe NDC to ask for

The same medicine as Apriso, without the brand name. Give the pharmacy its NDC to get it.

mesalamine

Sold by
  • Teva Pharmaceuticals
NDC to ask for
  • 375 mgextended-release capsule
    • 0093-9224-8911-digit: 00093-9224-89120 capsules per bottle

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Apriso, can you tell me what I’d pay for the brand, for the authorized generic from Teva Pharmaceuticals (NDC 0093-9224-89), and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

Apriso is sold under its generic name, so there’s no separate brand label to compare. Here’s its label.

Authorized genericTeva Pharmaceuticals
See the ingredients

Active: mesalamine 375 mg

Inactive:

  • Anhydrous citric acid
  • Aspartame
  • Crospovidone
  • Hypromellose
  • Magnesium stearate
  • Methacrylic acid - methyl methacrylate copolymer
  • Microcrystalline cellulose
  • Povidone
  • Silicon dioxide
  • Talc
  • Titanium dioxide
  • Triethyl citrate

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic mesalamine, lowest first.

Delivered

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericWho makes it

6 companies sell a generic of Apriso that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • Alembic Pharmaceuticals375 mg

    Has dyes: FD&C Blue No. 1, FD&C Red No. 40

    How it looks, what’s in it, NDCs

    0.375 g Opaque light blue cap and opaque light blue body, capsule, 23 mm, marked “A / 255”

    PackageNDC
    Bottle of 12062332-724-35
    Bottle of 100062332-724-91

    Inactive ingredients: microcrystalline cellulose, hypromellose, silicon dioxide, ethyl acrylate and methyl methacrylate copolymer (2:1; 750000 mw), magnesium stearate, methacrylic acid - methyl methacrylate copolymer (1:1), talc, triethyl citrate, titanium dioxide, hypromellose phthalate (31% phthalate, 40 cst), FD&C Blue No. 1, FD&C Red No. 40, gelatin, shellac, ferrosoferric oxide, potassium hydroxide

    FDA label

  • Ascend Laboratories375 mg

    Has dyes: FD&C Blue No. 1, FD&C Red No. 3 · Made by Alkem Laboratories

    How it looks, what’s in it, NDCs

    0.375 g Blue, capsule, 24 mm, marked “MES / 375”

    PackageNDC
    Bottle of 12067877-717-12
    Bottle of 50067877-717-05

    Inactive ingredients: microcrystalline cellulose, hypromellose 2208 (4000 mpa.s), silicon dioxide, magnesium stearate, ethyl acrylate and methyl methacrylate copolymer (2:1; 750000 mw), methacrylic acid - methyl methacrylate copolymer (1:1), talc, triethyl citrate, hypromellose 2910 (5 mpa.s), titanium dioxide, polyethylene glycol 400, vanillin, gelatin, FD&C Blue No. 1, FD&C Red No. 3, shellac, ferrosoferric oxide, sodium lauryl sulfate, nonoxynol-100

  • Aurobindo Pharma375 mg

    Has dyes: D&C Red No. 22, FD&C Blue No. 1

    Product page on aurobindousa.com

    How it looks, what’s in it, NDCs

    0.375 g Light blue cap, light blue body, capsule, 24 mm, marked “MSM / 375”

    PackageNDC
    Bottle of 12059651-397-08

    Inactive ingredients: silicon dioxide, hypromellose 2208 (100 mpa.s), magnesium stearate, methacrylic acid - methyl methacrylate copolymer (1:1), sodium lauryl sulfate, microcrystalline cellulose 101, nonoxynol-100, ethyl acrylate and methyl methacrylate copolymer (2:1; 750000 mw), dimethicone, talc, titanium dioxide, triethyl citrate, D&C Red No. 22, FD&C Blue No. 1, gelatin, ferrosoferric oxide, potassium hydroxide, shellac

    FDA label

  • Mylan Pharmaceuticals375 mg

    Has a dye: FD&C Green No. 3

    Product page on viatris.com

    How it looks, what’s in it, NDCs

    0.375 g Light green opaque, capsule, 23 mm, marked “MYLAN / MSA / 375”

    PackageNDC
    Bottle of 1200378-1375-78

    Inactive ingredients: ferrosoferric oxide, ethylcellulose, FD&C Green No. 3, gelatin, hypromellose, methacrylic acid - methyl methacrylate copolymer (1:1), potassium hydroxide, propylene glycol, shellac, starch, corn, sucrose, talc, titanium dioxide, triethyl citrate, ammonia

    FDA label

  • Upsher-Smith Laboratories375 mg

    Has a dye: FD&C Blue No. 1 · Made by Amta Labs

    Product page on upsher-smith.com

    How it looks, what’s in it, NDCs

    0.375 g Opaque powder blue cap and body, capsule, 23 mm, marked “A / 375”

    PackageNDC
    Bottle of 1200832-6056-12

    Inactive ingredients: starch, corn, sucrose, hypromellose, talc, ethylcellulose, triethyl citrate, methacrylic acid - methyl methacrylate copolymer (1:1), sodium lauryl sulfate, silicon dioxide, shellac, potassium hydroxide, ferrosoferric oxide, gelatin, FD&C Blue No. 1, titanium dioxide

    FDA label

  • Zydus Lifesciences375 mg

    Has a dye: FD&C Blue No. 1

    How it looks, what’s in it, NDCs

    0.375 g Opaque blue cap and opaque blue body, capsule, 24 mm, marked “452”

    PackageNDC
    Bottle of 12068382-452-19

    Inactive ingredients: ethylcellulose (10 mpa.s), hypromellose 2910 (5 mpa.s), methacrylic acid - methyl methacrylate copolymer (1:1), talc, triethyl citrate, FD&C Blue No. 1, gelatin, water, sodium lauryl sulfate, titanium dioxide, ferrosoferric oxide, potassium hydroxide, propylene glycol, shellac, sucrose, starch, corn

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

What the FDA label says

APRISO is an aminosalicylate indicated for the maintenance of remission of ulcerative colitis in adults.

Source: the FDA label for Apriso (Salix Pharmaceuticals, Inc.), August 27, 2026. Full label on DailyMed 

Good to know