How do you pay?

How to pay the least

Ask for the cash price

Arcalyst

Arcalyst is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

  1. Ask your pharmacy for Arcalyst’s cash price, and one or two other pharmacies too.
  2. Arcalyst’s savings card works only with insurance from a job or one you bought.

Compare every option

Question
Brand nameArcalyst
Authorized genericrilonacept
Regular genericrilonacept
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldAsk the pharmacy
Same as Arcalyst?
The original
–
–

Brand nameThe maker’s card

Kiniksa Copay Assistance Program (Kiniksa OneConnect)

Savings card from Kiniksa Pharmaceuticals

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a month

Sign up on arcalyst.com 

Or call 1-833-546-4572.

In the maker’s words

“If you are eligible, the Kiniksa Copay Assistance Program may be able to help lower your out-of-pocket costs such as copays, coinsurance, and deductibles to as little as $0 per month.”

From the maker’s offer on arcalyst.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Arcalyst itself, from the same company, sold without the brand name, and usually for less. For now Arcalyst is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Arcalyst is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

ARCALYST (rilonacept) is an interleukin-1 blocker indicated for:

  • Treatment of Cryopyrin-Associated Periodic Syndromes (CAPS), including Familial Cold Autoinflammatory Syndrome (FCAS), and Muckle-Wells Syndrome (MWS) in adults and children 12 years and older
  • Maintenance of remission of Deficiency of Interleukin-1 Receptor Antagonist (DIRA) in adults and pediatric patients weighing 10 kg or more
  • Treatment of recurrent pericarditis (RP) and reduction in risk of recurrence in adults and children 12 years and older

Source: the FDA label for Arcalyst (Kiniksa Pharmaceuticals (UK), Ltd.), December 16, 2025. Full label on DailyMed 

Good to know