Brand-name prescription

Astagraf XL

tacrolimus

Compare your options

Compare	Astagraf XLBrand name	Authorized genericWithout the Astagraf XL name	Regular generictacrolimus
What pharmacies pay	from$2.88–5.71per capsule	Not sold	Other forms only
Same as Astagraf XL?	The original	–	–
Ways to save	Maker’s cardup to $3,000 off a yearwith commercial insurance	–	–
With insurance	Your plan’s brand co-pay	–	–

No authorized generic: There isn’t one.

Regular generic: The FDA has approved one in this form, but it isn’t in pharmacies yet. Other forms or strengths are sold, but switching to one would need a new prescription.

Prices are the average U.S. drugstores pay (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

The maker’s savings card

Rx Maker’s savings card Astellas

Astellas Copay Card Program

With commercial insurance

up to $3,000 off a year

No insurance

This card needs commercial insurance. The maker doesn’t list a cash price on this page.

The card pays up to $3,000 a year.

Get it on astellascares.com

In the maker’s words

“Eligible participants in the Copay Card Program ("Program") may receive annual savings up to $3000 for PROGRAF or ASTAGRAF XL.”

From the maker’s offer on astellascares.com, checked September 25, 2026. What you pay depends on your plan. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Before you use a discount card

Discount cards like GoodRx take money off the pharmacy’s cash price. For a brand-name drug, that price is often still high. With commercial insurance, Astagraf XL’s own card may bring it to up to $3,000 off a year.

Look up the discount-card price, then compare it with this estimate. You can use a maker’s card or a discount card, but usually not both on the same fill.

What pharmacies pay

The average U.S. drugstores pay for each strength (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Strength	Astagraf XL
0.5 mg capsuleper capsule	$2.88
1 mg capsuleper capsule	$5.71

Good to know

There’s no authorized generic of Astagraf XL.
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.