Astagraf XL savings card: up to $3,000 off a year with commercial insurance

Strength How many

How to pay the least

From

$110 for 30 capsules

Generic tacrolimus XL from Rx Outreach, by mail. Pick the strength on your label above for its own price.

Make a free account on rxoutreach.org. Ask your prescriber to send the prescription there, or Rx Outreach can transfer it.Open Rx Outreach
Order generic tacrolimus XL. It comes by mail.

Need it today? From $168.34 for 30 capsules with the free Team Cuban Card, at pharmacies that take it. Get the free card and show it there.

See the price and get the card

A regular generic has the same active ingredient as Astagraf XL, and the FDA requires it to work the same way.

Compare every option

Brand nameAstagraf XL

Authorized generictacrolimus

Regular generictacrolimus

What you’d pay

At least$86for 30 capsules; pharmacies pay this

Not soldThere isn’t one

From$110for 30 capsules at Rx Outreach

Same as Astagraf XL?

The original

–

Same active ingredientFillers and dyes can differ

Brand nameThe maker’s card

Astellas Copay Card Program

Savings card from Astellas

No insuranceNeeds insuranceNo cash price listed.

Insurance · up to $3,000 off a year

The card takes up to $3,000 a year off your co-pay.

In the maker’s words

“Eligible participants in the Copay Card Program ("Program") may receive annual savings up to $3000 for PROGRAF or ASTAGRAF XL.”

From the maker’s offer on astellascares.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Astagraf XL itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.

See the regular generic →

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic tacrolimus, lowest first.

Pick up in storeDelivered

Delivered: Rx Outreach $110for 30 tablets1 mgFree delivery
Pick up in store: Team Cuban Card from $168.34for 30 capsules1 mg $168.34 · 5 mg $789.34Free card · Kroger, Albertsons, Safeway, Meijer and many local pharmaciesFind a pharmacy that takes it
Pick up in store: Walgreens + Optum Perks $113for 15 capsules5 mgFree Optum Perks coupon · not with insuranceFind the nearest store
Pick up in store: CVS Pharmacy + Optum Perks $155for 15 capsules5 mgFree Optum Perks coupon · not with insuranceFind the nearest store

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericWho makes it

One company sells a generic of Astagraf XL that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

It’s mostly filled by specialty pharmacies. Your prescriber’s office or insurer can tell you which one to use.

Amneal PharmaceuticalsAll 3 strengths

Has lactose · Made by Chengdu Suncadia Medicine

How it looks, what’s in it, NDCs

0.5 mg Opaque yellowish pink cap and opaque light orange body, capsule, 11 mm, marked “SD / TC / 0 / 5 / mg”

Package NDC
Carton of 30 69238-2780-3

1 mg Opaque light yellow cap and opaque light orange body, capsule, 14 mm, marked “SD / TC / 1 / mg”

Package NDC
Carton of 30 69238-2781-3

5 mg Opaque red-orange cap and opaque orange body, capsule, 21 mm, marked “SD / TC / 5 / mg”

Package NDC
Carton of 30 69238-2782-3

Inactive ingredients: ethylcellulose, hypromelloses, magnesium stearate, lactose monohydrate, gelatin, ferric oxide red, ferric oxide yellow, titanium dioxide
FDA label

Package	NDC
Carton of 30	69238-2780-3

Package	NDC
Carton of 30	69238-2781-3

Package	NDC
Carton of 30	69238-2782-3

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What to say at the pharmacy

“Before you fill my Astagraf XL, can you tell me what I’d pay for the brand and for a generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

What it’s used for

Preventing kidney transplant rejection

What the FDA label says

ASTAGRAF XL is a calcineurin-inhibitor immunosuppressant indicated for the prophylaxis of organ rejection in kidney transplant patients in combination with other immunosuppressants in adult and pediatric patients who can swallow capsules intact.

Source: the FDA label for Astagraf XL (Astellas Pharma US, Inc.), January 14, 2026. Full label on DailyMed

Good to know

A regular generic may look different from Astagraf XL. The FDA requires it to work the same way.
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/astagraf-xl/