How do you pay?

How to pay the least

Cash price

$590+ for 30 tablets

Pharmacies pay about this for Auvelity; you’d pay more.

  1. Ask your pharmacy for Auvelity’s cash price, and one or two other pharmacies too.
  2. Auvelity’s savings card works only with insurance from a job or one you bought.

No generic is sold yet.

Compare every option

Question
Brand nameAuvelity
Authorized genericdextromethorphan and bupropion
Regular genericdextromethorphan and bupropion
What you’d pay
At least$590for 30 tablets; pharmacies pay this
Not soldThere isn’t one
Not soldNone sold yet
Same as Auvelity?
The original
–
–

Brand nameThe maker’s card

AUVELITY On My Side Savings & Support Program

Savings card from Axsome Therapeutics

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $10 a fill

Sign up on auvelity.com 

Or text SAVE to 61489.

In the maker’s words

“You may be able to get up to 2 fills (a total of 120 tablets) of AUVELITY for as little as $10 per fill if your insurance does not cover AUVELITY.”

From the maker’s offer on auvelity.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Auvelity itself, from the same company, sold without the brand name, and usually for less. For now Auvelity is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

No generic is sold yet. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

AUVELITY is a combination of dextromethorphan, an uncompetitive N-methyl D-aspartate (NMDA) receptor antagonist and sigma-1 receptor agonist, and bupropion, an aminoketone and CYP450 2D6 inhibitor, indicated for

  • the treatment of major depressive disorder (MDD) in adults
  • the treatment of agitation associated with dementia due to Alzheimer’s disease

Limitations of Use: AUVELITY is not indicated as an as needed (“prn”) treatment for agitation associated with dementia due to Alzheimer’s disease.

Source: the FDA label for Auvelity (Axsome Therapeutics, Inc.), August 17, 2026. Full label on DailyMed 

Good to know