Ayvakit

Generic name: avapritinib

Used for: Systemic mastocytosis (advanced or slow-growing) · Advanced digestive tract tumor (GIST) with a PDGFRA exon 18 mutation · 1 more

How do you pay?

How to pay the least

Ask for the cash price

Ayvakit

We didn’t find one.

  1. Ask your pharmacy for Ayvakit’s cash price, and one or two other pharmacies too.
  2. Ayvakit’s savings card works only with insurance from a job or one you bought.

Compare every option

Question
Brand nameAyvakit
Authorized genericavapritinib
Regular genericavapritinib
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldNone found
Same as Ayvakit?
The original
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–

Brand nameThe maker’s card

AYVAKIT Co-Pay Assistance Program (YourBlueprint)

Savings card from Blueprint Medicines

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a month

Sign up on ayvakit.com 

Or call 1-888-258-7768.

In the maker’s words

“If you have commercial insurance through your job, a partner's job or buy it yourself, you may be eligible to pay as little as $0 per month for your prescription.”

From the maker’s offer on ayvakit.com, checked October 26, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Ayvakit itself, from the same company, sold without the brand name, and usually for less. For now Ayvakit is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

We didn’t find one. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

AYVAKIT is a kinase inhibitor indicated for:

Gastrointestinal Stromal Tumor (GIST)

  • the treatment of adults with unresectable or metastatic GIST harboring a platelet-derived growth factor receptor alpha (PDGFRA) exon 18 mutation, including PDGFRA D842V mutations.

Advanced Systemic Mastocytosis (AdvSM)

  • the treatment of adult patients with AdvSM. AdvSM includes patients with aggressive systemic mastocytosis (ASM), systemic mastocytosis with an associated hematological neoplasm (SM-AHN), and mast cell leukemia (MCL).
  • Limitations of Use: AYVAKIT is not recommended for the treatment of patients with AdvSM with platelet counts of less than 50 × 109/L

Indolent Systemic Mastocytosis (ISM)

  • the treatment of adult patients with ISM.
  • Limitations of Use: AYVAKIT is not recommended for the treatment of patients with ISM with platelet counts of less than 50 × 109/L

Source: the FDA label for Ayvakit (Blueprint Medicines Corporation), September 14, 2026. Full label on DailyMed 

Good to know

Prices checked October 26, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/ayvakit/