How to pay the least
Lowest to pick up today
$14.25 for 30 tablets
Generic sulfamethoxazole and trimethoprim 400 mg / 80 mg with the free Team Cuban Card, at pharmacies that take it
- Get the free Team Cuban Card. It costs nothing to sign up.See the price and get the card
- At a pharmacy that takes it, show the card and ask for generic sulfamethoxazole and trimethoprim 400 mg / 80 mg.Find a pharmacy that takes it
By mail, if you can wait a few days $11.39 for 30 tablets delivered ($6.14 plus $5.25 shipping) from Cost Plus Drugs. Make a free account, then have your prescription sent there.
Open Cost Plus DrugsA regular generic has the same active ingredient as Bactrim, and the FDA requires it to work the same way.
Compare every option
Details for each option
Brand nameNo maker’s card
We didn’t find a savings card or cash price from Bactrim’s maker. Ask the pharmacy for Bactrim’s cash price. With insurance, ask what your plan charges.
Authorized genericNot sold
There isn’t one. An authorized generic is Bactrim itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.
Regular genericWhere to buy it
Pharmacies’ own cash prices for generic sulfamethoxazole and trimethoprim, lowest first.
Pick up in storeDelivered
- Delivered: Cost Plus Drugs $6.14for 30 tablets400 mg / 80 mgPlus $5.25 shipping
- Pick up in store: Team Cuban Card $14.25for 30 tablets400 mg / 80 mgFree card · Kroger, Albertsons, Safeway, Meijer and many local pharmaciesFind a pharmacy that takes it
From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.
About these prices
Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.
Regular genericWho makes it
4 companies sell a generic of Bactrim that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.
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Amneal Pharmaceuticals400 mg / 80 mg
How it looks, what’s in it, NDCs
400 mg / 80 mg White, oval, 13 mm, marked “IP / 271”
Package NDC Bottle of 50 53746-271-50 Bottle of 100 53746-271-01 Bottle of 500 53746-271-05 Bottle of 1000 53746-271-10 400 mg / 80 mg White, round, 13 mm, marked “IP / 271”
Package NDC Bottle of 50 65162-271-05 Bottle of 100 65162-271-10 Bottle of 500 65162-271-50 Bottle of 1000 65162-271-11 Inactive ingredients: magnesium stearate, povidone, starch, corn, sodium starch glycolate type a potato
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Aurobindo Pharma400 mg / 80 mg
Product page on aurobindousa.com
How it looks, what’s in it, NDCs
400 mg / 80 mg White to Off-white, round, 11 mm, marked “H / 48”
Package NDC Bottle of 20 65862-419-20 Bottle of 100 65862-419-01 Bottle of 500 65862-419-05 Bottle of 1000 65862-419-99 Inactive ingredients: docusate sodium, magnesium stearate, starch, corn, sodium benzoate, sodium starch glycolate type a potato
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Chartwell RX400 mg / 80 mg
How it looks, what’s in it, NDCs
400 mg / 80 mg White to off white, round, 11 mm, marked “CE / 103”
Package NDC Bottle of 90 62135-897-90 Bottle of 180 62135-897-18 Inactive ingredients: starch, corn, docusate sodium, povidone, sodium starch glycolate type a potato, magnesium stearate
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Rising Pharma Holdings400 mg / 80 mg
Made by Aurobindo Pharma
How it looks, what’s in it, NDCs
400 mg / 80 mg White to Off-white, round, 11 mm, marked “H / 48”
Package NDC Bottle of 100 57237-232-01 Bottle of 500 57237-232-05 Inactive ingredients: docusate sodium, magnesium stearate, starch, corn, sodium benzoate, sodium starch glycolate type a potato
Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.
What to say at the pharmacy
“Before you fill my Bactrim, can you tell me what I’d pay for the brand and for a generic?”
Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.
What it’s used for
- Urinary tract infections
- Ear infections
- Flare-ups of chronic bronchitis
- Treating and preventing Pneumocystis pneumonia
- Traveler’s diarrhea
- Bowel infection from Shigella (shigellosis)
What the FDA label says
To reduce the development of drug-resistant bacteria and maintain the effectiveness of BACTRIM (sulfamethoxazole and trimethoprim) tablets and other antibacterial drugs, BACTRIM (sulfamethoxazole and trimethoprim) tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to empiric selection of therapy.
Urinary Tract Infections
For the treatment of urinary tract infections due to susceptible strains of the following organisms: Escherichia coli, Klebsiellaspecies, Enterobacterspecies, Morganella morganii, Proteus mirabilisand Proteus vulgaris. It is recommended that initial episodes of uncomplicated urinary tract infections be treated with a single effective antibacterial agent rather than the combination.
Acute Otitis Media
For the treatment of acute otitis media in pediatric patients due to susceptible strains of Streptococcus pneumoniaeor Haemophilus influenzaewhen in the judgment of the physician sulfamethoxazole and trimethoprim offers some advantage over the use of other antimicrobial agents. To date, there are limited data on the safety of repeated use of BACTRIM in pediatric patients under two years of age. BACTRIM is not indicated for prophylactic or prolonged administration in otitis media at any age.
Acute Exacerbations of Chronic Bronchitis in Adults
For the treatment of acute exacerbations of chronic bronchitis due to susceptible strains of Streptococcus pneumoniaeor Haemophilus influenzaewhen a physician deems that BACTRIM could offer some advantage over the use of a single antimicrobial agent.
Shigellosis
For the treatment of enteritis caused by susceptible strains of Shigella flexneriand Shigella sonneiwhen antibacterial therapy is indicated.
Pneumocystis jiroveciiPneumonia
For the treatment of documented Pneumocystis jiroveciipneumonia and for prophylaxis against P. jiroveciipneumonia in individuals who are immunosuppressed and considered to be at an increased risk of developing P. jiroveciipneumonia.
Traveler's Diarrhea in Adults
For the treatment of traveler's diarrhea due to susceptible strains of enterotoxigenic E. coli.
Source: the FDA label for Bactrim (Sun Pharmaceutical Industries, Inc), December 30, 2024. Full label on DailyMed
Good to know
- A regular generic may look different from Bactrim. The FDA requires it to work the same way.
- We didn’t find a savings card from Bactrim’s maker.
- Don’t stop or change a medicine without talking to your pharmacist or prescriber.
Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/bactrim/