How do you pay?

How to pay the least

Ask for the cash price

BeneFIX

BeneFIX is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

  1. Ask your pharmacy for BeneFIX’s cash price, and one or two other pharmacies too.
  2. BeneFIX’s savings card works only with insurance from a job or one you bought.

Free from the maker, if you qualify Pfizer Patient Assistance Program. Meet the income requirements – Your annual household pre-tax income cannot exceed 300% of the Federal Poverty Level, adjusted for household size. Or call 1-844-989-7284.

See if you qualify 

Compare every option

Question
Brand nameBeneFIX
Authorized genericcoagulation factor ix (recombinant)
Regular genericcoagulation factor ix (recombinant)
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldAsk the pharmacy
Same as BeneFIX?
The original
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–

Brand nameThe maker’s card

Pfizer Factor Savings Card (Pfizer Hemophilia Connect)

Savings card from Pfizer

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a fill

The card takes up to $12,000 a year off your co-pay.

Sign up on pfizerhemophiliasupport.com 

Or call 1-888-733-2030.

In the maker’s words

“Eligible patients with commercial prescription drug insurance coverage for BeneFIX or Xyntha may pay as little as $0 per prescription fill.”

From the maker’s offer on pfizerhemophiliasupport.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is BeneFIX itself, from the same company, sold without the brand name, and usually for less. For now BeneFIX is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

BeneFIX is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

BeneFIX is a recombinant human blood coagulation factor IX indicated for adults and children with hemophilia B (congenital factor IX deficiency or Christmas disease) for:

  • On-demand treatment and control of bleeding episodes.
  • Perioperative management of bleeding.
  • Routine prophylaxis to reduce the frequency of bleeding episodes.

Limitations of Use

BeneFIX is not indicated for induction of immune tolerance in patients with hemophilia B.

Source: the FDA label for BeneFIX (Wyeth BioPharma Division of Wyeth Pharmaceuticals LLC), February 24, 2025. Full label on DailyMed 

Good to know