Bethkis vs. its authorized generic and generics

How to pay the least

Ask for the cash price

Generic tobramycin

No pharmacy we check posts a price for it.

Ask your pharmacy for the cash price of generic tobramycin.Find pharmacies near you
Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Bethkis, and the FDA requires it to work the same way.

Compare every option

Brand nameBethkis

Authorized generictobramycin

Regular generictobramycin

What you’d pay

Cash priceAsk the pharmacyUsually the highest price

Cash priceAsk the pharmacyOften less than Bethkis

Cash priceAsk the pharmacyUsually the lowest

Same as Bethkis?

The original

Same medicine

Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Bethkis’s maker. Ask the pharmacy for Bethkis’s cash price. With insurance, ask what your plan charges.

Authorized genericThe NDC to ask for

The same medicine as Bethkis, without the brand name. Give the pharmacy its NDC to get it.

tobramycin

Sold by

Prasco

NDC to ask for

300 mg/4 mLsolution
- 66993-195-9411-digit: 66993-0195-9456 ampules, 4 mL each

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Bethkis, can you tell me what I’d pay for the brand, for the authorized generic from Prasco (NDC 66993-195-94), and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

Same active and inactive ingredients as Bethkis.

Authorized generic package label from Prasco — Authorized genericPrasco

See the ingredients

Active: tobramycin 300 mg/4 mL

Inactive, on both labels:

Sodium chloride
Sodium hydroxide
Sulfuric acid
Water

Regular genericWho makes it

One company sells a generic of Bethkis that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

It’s mostly filled by specialty pharmacies. Your prescriber’s office or insurer can tell you which one to use.

NorthStar Rx300 mg/4 mL

Made by Mankind Pharma

Product page on northstarrxllc.com

How it looks, what’s in it, NDCs

300 mg/4 mL

Package NDC
Carton of 224 mL 72603-630-56

Inactive ingredients: sodium chloride, sulfuric acid, water, sodium hydroxide

Package	NDC
Carton of 224 mL	72603-630-56

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

Pseudomonas lung infection in cystic fibrosis

What the FDA label says

BETHKIS is an inhaled aminoglycoside antibacterial indicated for the management of cystic fibrosis patients with Pseudomonas aeruginosa. Safety and efficacy have not been demonstrated in patients under the age of six years, patients with a forced expiratory volume in one second (FEV1) less than 40% or greater than 80% predicted, or patients colonized with Burkholderia cepacia.

Source: the FDA label for Bethkis (Chiesi USA, Inc.), February 24, 2023. Full label on DailyMed

Good to know

It may look different from Bethkis (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Cash prices can differ a lot from one pharmacy to the next, so it can pay to ask two. With insurance, what you pay depends on your plan.
If your pharmacy doesn’t stock it, they can often order it within a day or two.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/bethkis/