Brevibloc vs. its authorized generic and generics

Brevibloc is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How to pay the least

Given by your care team

Billed by the clinic

Brevibloc is given by a doctor or nurse, not picked up at a pharmacy.

Ask your care team or your plan what you’d pay before your visit.

Compare every option

Brand nameBrevibloc

Authorized genericesmolol

Regular genericesmolol

What you’d pay

Cash priceAsk the pharmacyUsually the highest price

Cash priceAsk the pharmacyOften less than Brevibloc

Cash priceAsk the pharmacyUsually the lowest

Same as Brevibloc?

The original

Same medicine

Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Brevibloc’s maker. Ask the pharmacy for Brevibloc’s cash price. With insurance, ask what your plan charges.

Authorized genericThe NDC to ask for

The same medicine as Brevibloc, without the brand name. Give the pharmacy its NDC to get it.

esmolol

Sold by

Baxter HealthcareThe company behind Brevibloc

Given by your care team

This is given by IV in the hospital, not picked up at a pharmacy.

NDC (for your care team)

10 mg/mLinjection
- 10019-120-0111-digit: 10019-0120-0125 vials, 10 mL each

Source: FDA, updated October 30, 2026

What to ask your care team

“Which version of Brevibloc do you use: the brand, the authorized generic or a regular generic? What would I pay for each?”

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

Same active and inactive ingredients as Brevibloc.

Brevibloc package label — BrandBrevibloc

Authorized generic package label from Baxter Healthcare — Authorized genericBaxter Healthcare

See the ingredients

Active: esmolol hydrochloride 10 mg/mL

Inactive, on both labels:

Acetic acid
Hydrochloric acid
Sodium acetate
Sodium chloride
Sodium hydroxide
Water

Regular genericWho makes it

5 companies sell an FDA-rated generic of Brevibloc. It’s given by your care team, who choose which one to use.

Amneal PharmaceuticalsInjection 10 mg/mL, 20 mg/mL

How it looks, what’s in it, NDCs

10 mg/mL

Package NDC
Carton of 2500 mL 70121-1716-7
Carton of 3000 mL 70121-1716-3

20 mg/mL

Package NDC
Carton of 1000 mL 70121-1717-7
Carton of 1200 mL 70121-1717-3

Inactive ingredients: acetic acid, hydrochloric acid, sodium acetate, sodium chloride, sodium hydroxide, water
FDA label
EugiaInjection 10 mg/mL, 20 mg/mL · Solution 100 mg/10 mL

Product page on eugiaus.com

How it looks, what’s in it, NDCs

10 mg/mL

Package NDC
Carton of 2500 mL 55150-420-10

20 mg/mL

Package NDC
Carton of 1000 mL 55150-421-10

100 mg/10 mL

Package NDC
Carton of 250 mL 55150-194-10

Inactive ingredients: sodium acetate, sodium chloride, acetic acid, water, sodium hydroxide, hydrochloric acid
FDA label
Mylan InstitutionalSolution 10 mg/mL · Injection 10 mg/mL, 20 mg/mL

How it looks, what’s in it, NDCs

10 mg/mL

Package NDC
Carton of 100 mL 67457-182-10

10 mg/mL

Package NDC
Pouch of 250 mL 67457-657-25

20 mg/mL

Package NDC
Pouch of 100 mL 67457-658-10

Inactive ingredients: sodium acetate anhydrous, acetic acid, sodium hydroxide, hydrochloric acid, water, sodium chloride, sodium acetate
FDA label
Sagent PharmaceuticalsSolution 10 mg/mL, 20 mg/mL

Product page on sagentpharma.com

How it looks, what’s in it, NDCs

10 mg/mL

Package NDC
Carton of 2500 mL 25021-308-84

20 mg/mL

Package NDC
Carton of 1000 mL 25021-309-82

Inactive ingredients: sodium acetate, acetic acid, sodium chloride, hydrochloric acid, sodium hydroxide, water
FDA label
WG Critical CareInjection 10 mg/mL, 20 mg/mL

Made by HQ Specialty Pharma

Product page on wgcriticalcare.com

Packages and NDCs

10 mg/mL

Package NDC
Carton of 2500 mL 44567-450-10

20 mg/mL

Package NDC
Carton of 1000 mL 44567-451-10

Package	NDC
Carton of 2500 mL	70121-1716-7
Carton of 3000 mL	70121-1716-3

Package	NDC
Carton of 1000 mL	70121-1717-7
Carton of 1200 mL	70121-1717-3

Package	NDC
Carton of 2500 mL	55150-420-10

Package	NDC
Carton of 1000 mL	55150-421-10

Package	NDC
Carton of 250 mL	55150-194-10

Package	NDC
Carton of 100 mL	67457-182-10

Package	NDC
Pouch of 250 mL	67457-657-25

Package	NDC
Pouch of 100 mL	67457-658-10

Package	NDC
Carton of 2500 mL	25021-308-84

Package	NDC
Carton of 1000 mL	25021-309-82

Package	NDC
Carton of 2500 mL	44567-450-10

Package	NDC
Carton of 1000 mL	44567-451-10

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

What the FDA label says

BREVIBLOC injection is a beta adrenergic blocker indicated for the short-term treatment of:

Control of ventricular rate in supraventricular tachycardia including atrial fibrillation and atrial flutter and control of heart rate in noncompensatory sinus tachycardia
Control of perioperative tachycardia and hypertension

Source: the FDA label for Brevibloc (Baxter Healthcare Company), March 14, 2025. Full label on DailyMed

Good to know

It may look different from Brevibloc (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Coverage depends on your plan. Your care team or insurer can tell you what you’d pay.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/brevibloc/