How do you pay?

Match the strength and how many to your prescription label.

How to pay the least

Ask for the cash price

Generic butalbital, acetaminophen, and caffeine

Only Amazon Pharmacy posts a price for butalbital, acetaminophen, and caffeine 50 mg / 325 mg / 40 mg, 30 tablets, and it’s for members. Pharmacies pay about $3.66 for 30 tablets; cash prices are higher. Ask two or three.

  1. Ask your pharmacy: “What’s your cash price for generic butalbital, acetaminophen, and caffeine 50 mg / 325 mg / 40 mg, 30 tablets?”Find pharmacies near you
  2. Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

With a membership $11.57 for 30 tablets from Amazon Pharmacy, by mail ($139 a year).

Open Amazon Pharmacy

Every company’s butalbital, acetaminophen, and caffeine is rated by the FDA to work the same, so any pharmacy can fill your prescription with the one it stocks.

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic butalbital, acetaminophen, and caffeine, lowest first. Any of them can fill your prescription.

Delivered

From each pharmacy’s own site, read October 5, 2026. Confirm the price before you fill. Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericWho makes it

8 companies sell butalbital, acetaminophen, and caffeine in this form, each one rated by the FDA as a substitute for the others. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What to say at the pharmacy

“Before you fill it, what would I pay for generic butalbital, acetaminophen, and caffeine?”

Paying cash? Ask for the cash price. With insurance, ask what your plan charges.

Good to know