Casporyn HC vs. its authorized generic and generics

How to pay the least

Ask for the cash price

Generic neomycin, polymyxin B, and hydrocortisone

No pharmacy we check posts a price for it.

Ask your pharmacy for the cash price of generic neomycin, polymyxin B, and hydrocortisone.Find pharmacies near you
Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Casporyn HC, and the FDA requires it to work the same way.

Compare every option

Brand nameCasporyn HC

Authorized genericneomycin, polymyxin B, and hydrocortisone

Regular genericneomycin, polymyxin B, and hydrocortisone

What you’d pay

Not soldNo longer sold

Cash priceAsk the pharmacyUsually among the lowest

Same as Casporyn HC?

–

Same medicine

Same active ingredientFillers and dyes can differ

Brand nameNot sold

Casporyn HC itself isn’t sold as a prescription anymore. Its generic versions, if any, are in the other tabs.

See the authorized generic →

Authorized genericThe NDC to ask for

The same medicine as Casporyn HC, without the brand name. Give the pharmacy its NDC to get it.

neomycin, polymyxin B, and hydrocortisone

Sold by

Rising Pharma Holdings

NDC to ask for

10 mg/mL / 3.5 mg/mL / 10,000 units/mLsuspension
- 64980-448-0111-digit: 64980-0448-0110 mL per bottle

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Casporyn HC, can you tell me what I’d pay for the brand, for the authorized generic from Rising Pharma Holdings (NDC 64980-448-01), and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

Casporyn HC itself isn’t sold anymore, so there’s no current brand label to compare. Here’s the authorized generic’s label.

Authorized generic package label from Rising Pharma Holdings — Authorized genericRising Pharma Holdings

See the ingredients

Active: hydrocortisone 10 mg/mL · neomycin sulfate 3.5 mg/mL · polymyxin B sulfate 10,000 units/mL

Inactive:

Cetyl alcohol
Polysorbate 80
Propylene glycol
Sulfuric acid
Thimerosal
Water

Regular genericWho makes it

2 companies sell a generic of Casporyn HC that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

Bausch & Lomb10 mg/mL / 3.5 mg/mL / 10,000 units/mL

Sold as Neomycin and Polymyxin B Sulfates and Hydrocortisone

How it looks, what’s in it, NDCs

10 mg/mL / 3.5 mg/mL / 10,000 units/mL

Package NDC
Carton of 10 mL 24208-635-62

Inactive ingredients: cetyl alcohol, polysorbate 80, propylene glycol, water, sulfuric acid, thimerosal
FDA label
Sandoz3.5 mg/mL / 10,000 units/mL / 10 mg/mL

Sold as Neomycin and Polymyxin B Sulfates and Hydrocortisone

How it looks, what’s in it, NDCs

3.5 mg/mL / 10,000 units/mL / 10 mg/mL

Package NDC
Bottle of 10 mL 61314-645-11

Inactive ingredients: thimerosal, cetyl alcohol, propylene glycol, polysorbate 80, acetic acid, water
FDA label

Package	NDC
Carton of 10 mL	24208-635-62

Package	NDC
Bottle of 10 mL	61314-645-11

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

Outer ear infections (swimmer’s ear)
Infections after ear surgery (mastoidectomy)

What the FDA label says

For the treatment of superficial bacterial infections of the external auditory canal caused by organisms susceptible to the action of the antibiotics, and for the treatment of infections of mastoidectomy and fenestration cavities caused by organisms susceptible to the antibiotics.

Source: the FDA label for Neomycin and Polymyxin B Sulfates and Hydrocortisone Otic Suspension (Rising Pharma Holdings, Inc.), June 10, 2024. Full label on DailyMed

Good to know

It may look different from Casporyn HC (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Cash prices can differ a lot from one pharmacy to the next, so it can pay to ask two. With insurance, what you pay depends on your plan.
If your pharmacy doesn’t stock it, they can often order it within a day or two.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/casporyn-hc/