Cinryze is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How do you pay?

How to pay the least

Given by your care team

Billed by the clinic

Cinryze is given by a doctor or nurse, not picked up at a pharmacy.

  1. Ask your care team or your plan what you’d pay before your visit.

Compare every option

Question
Brand nameCinryze
Authorized generichuman c1-esterase inhibitor
Regular generichuman c1-esterase inhibitor
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldAsk the pharmacy
Same as Cinryze?
The original
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–

Brand nameThe maker’s card

Takeda Patient Support Co-Pay Assistance Program

Savings card from Takeda

No insuranceNeeds insuranceNo cash price listed.
Insurance · up to $40,000 off a year

The card takes up to $40,000 a year off your co-pay.

Sign up on takedapatientsupport.com 

In the maker’s words

“The maximum co-pay assistance available annually is $20,000 ($40,000 for hereditary angioedema treatment, $10,000 for cytomegalovirus).”

From the maker’s offer on takedapatientsupport.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericNot sold

There isn’t one. An authorized generic is Cinryze itself, from the same company, sold without the brand name, and usually for less. For now Cinryze is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Cinryze is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

CINRYZE is a C1 esterase inhibitor indicated for routine prophylaxis against angioedema attacks in adults, adolescents, and pediatric patients (6 years of age and older) with Hereditary Angioedema (HAE).

Source: the FDA label for Cinryze (Takeda Pharmaceuticals America, Inc.), November 28, 2025. Full label on DailyMed 

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