Climara vs. its authorized generic and generics | DrugAlt

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How to pay the least

Ask for the cash price

Generic estradiol

No pharmacy we check posts a price for it.

Ask your pharmacy for the cash price of generic estradiol.Find pharmacies near you
Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Climara, and the FDA requires it to work the same way.

Compare every option

Brand nameClimara

Authorized genericestradiol

Regular genericestradiol

What you’d pay

Cash priceAsk the pharmacyUsually the highest price

Cash priceAsk the pharmacyUsually less than Climara

Cash priceAsk the pharmacyUsually the lowest

Same as Climara?

The original

Same medicine

Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Climara’s maker. Ask the pharmacy for Climara’s cash price. With insurance, ask what your plan charges.

Authorized genericThe NDC to ask for

The same medicine as Climara, without the brand name. Give the pharmacy its NDC to get it.

estradiol

Sold by

Sandoz

Your strength

NDC to ask for

0.025 mg/daypatch
- 0781-7119-5411-digit: 00781-7119-544 patches per carton
0.0375 mg/daypatch
- 0781-7122-5411-digit: 00781-7122-544 patches per carton
0.05 mg/daypatch
- 0781-7133-5411-digit: 00781-7133-544 patches per carton
0.06 mg/daypatch
- 0781-7134-5411-digit: 00781-7134-544 patches per carton
0.075 mg/daypatch
- 0781-7136-5411-digit: 00781-7136-544 patches per carton
0.1 mg/daypatch
- 0781-7104-5411-digit: 00781-7104-544 patches per carton

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Climara, can you tell me what I’d pay for the brand, for the authorized generic from Sandoz, and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

0.1 mg/day patch

Same active ingredient as Climara. Climara’s label doesn’t list its inactive ingredients, so those can’t be compared.

Climara package label — BrandClimara

Authorized generic package label from Sandoz — Authorized genericSandoz

See the ingredients

Active: estradiol 0.1 mg/day

0.025 mg/day patch

Same active ingredient as Climara. Climara’s label doesn’t list its inactive ingredients, so those can’t be compared.

Climara package label — BrandClimara

Authorized generic package label from Sandoz — Authorized genericSandoz

See the ingredients

Active: estradiol 0.025 mg/day

0.0375 mg/day patch

Same active ingredient as Climara. Climara’s label doesn’t list its inactive ingredients, so those can’t be compared.

Climara package label — BrandClimara

Authorized generic package label from Sandoz — Authorized genericSandoz

See the ingredients

Active: estradiol 0.0375 mg/day

0.05 mg/day patch

Same active ingredient as Climara. Climara’s label doesn’t list its inactive ingredients, so those can’t be compared.

Climara package label — BrandClimara

Authorized generic package label from Sandoz — Authorized genericSandoz

See the ingredients

Active: estradiol 0.05 mg/day

0.06 mg/day patch

Same active ingredient as Climara. Climara’s label doesn’t list its inactive ingredients, so those can’t be compared.

Climara package label — BrandClimara

Authorized generic package label from Sandoz — Authorized genericSandoz

See the ingredients

Active: estradiol 0.06 mg/day

0.075 mg/day patch

Same active ingredient as Climara. Climara’s label doesn’t list its inactive ingredients, so those can’t be compared.

Climara package label — BrandClimara

Authorized generic package label from Sandoz — Authorized genericSandoz

See the ingredients

Active: estradiol 0.075 mg/day

Regular genericWho makes it

One company sells a generic of Climara that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

Mylan PharmaceuticalsAll 6 strengths

Product page on viatris.com

How it looks, what’s in it, NDCs

0.025 mg/day

Package NDC
Carton of 28 0378-3349-99

0.0375 mg/day

Package NDC
Carton of 28 0378-3360-99

0.05 mg/day

Package NDC
Carton of 28 0378-3350-99

0.06 mg/day

Package NDC
Carton of 28 0378-3361-99

0.075 mg/day

Package NDC
Carton of 28 0378-3351-99

0.1 mg/day

Package NDC
Carton of 28 0378-3352-99

Inactive ingredients: propylene glycol, povidone, silicon dioxide
FDA label

The FDA doesn’t rate Amneal Pharmaceuticals’s version of estradiol a substitute for Climara, so a pharmacy can’t swap it in without your prescriber’s OK.

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

What the FDA label says

Climara is an estrogen indicated for:

Treatment of Moderate to Severe Vasomotor Symptoms due to Menopause
Treatment of Moderate to Severe Symptoms of Vulvar and Vaginal Atrophy due to Menopause Limitations of Use When prescribing solely for the treatment of moderate to severe symptoms of vulvar and vaginal atrophy due to menopause, first consider the use of topical vaginal products.
Treatment of Hypoestrogenism due to Hypogonadism, Castration or Primary Ovarian Failure
Prevention of Postmenopausal Osteoporosis Limitations of Use When prescribing solely for the prevention of postmenopausal osteoporosis, first consider the use of non-estrogen medications. Consider estrogen therapy only for women at significant risk of osteoporosis.

Source: the FDA label for Climara (Bayer HealthCare Pharmaceuticals Inc.), March 26, 2026. Full label on DailyMed

Good to know

It may look different from Climara (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Cash prices can differ a lot from one pharmacy to the next, so it can pay to ask two. With insurance, what you pay depends on your plan.
If your pharmacy doesn’t stock it, they can often order it within a day or two.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/climara/