Clobex vs. its authorized generic and generics

How to pay the least

Ask for the cash price

Generic clobetasol

No pharmacy we check posts a price for it.

Ask your pharmacy for the cash price of generic clobetasol.Find pharmacies near you
Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Clobex, and the FDA requires it to work the same way.

Compare every option

Brand nameClobex

Authorized genericclobetasol

Regular genericclobetasol

What you’d pay

Not soldNo longer sold

Cash priceAsk the pharmacyUsually among the lowest

Same as Clobex?

–

Same medicine

Same active ingredientFillers and dyes can differ

Brand nameNot sold

Clobex itself isn’t sold as a prescription anymore. Its generic versions, if any, are in the other tabs.

See the authorized generic →

Authorized genericThe NDC to ask for

The same medicine as Clobex, without the brand name. Give the pharmacy its NDC to get it.

clobetasol

Sold by

Mayne Pharma

NDC to ask for

0.05%shampoo
- 68308-664-0411-digit: 68308-0664-04118 mL per bottle

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Clobex, can you tell me what I’d pay for the brand, for the authorized generic from Mayne Pharma (NDC 68308-664-04), and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

Clobex itself isn’t sold anymore, so there’s no current brand label to compare. Here’s the authorized generic’s label.

See the ingredients

Active: clobetasol propionate 0.05%

Inactive:

Alcohol
Citric acid monohydrate
Coco-betaine
Polyquaternium-10
Sodium citrate
Sodium laureth sulfate
Water

Regular genericMakers and their savings programs

10 companies sell a generic of Clobex that the FDA rates a substitute. A pharmacy fills whichever one it stocks. One of them has its own savings program, listed first. It works only with that maker’s version. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

Medimetriks PharmaceuticalsShampoo 0.05%

Sold as Clodan · Made by Padagis

Medimetriks Patient Money Back Guarantee

“We offer patients a 100% Money Back Guarantee on all of our brands.” (anyone who paid out of pocket (return unused product with proof of purchase))

See the program

How it looks, what’s in it, NDCs

0.05% White

Package NDC
Carton of 118 mL 43538-950-04

Inactive ingredients: alcohol, hydrochloric acid, coco-betaine, sodium laureth-3 sulfate, water, polyquaternium-10 (400 mpa.s at 2%)
FDA label
Actavis PharmaLotion 0.05%

How it looks, what’s in it, NDCs

0.05%

Package NDC
Carton of 59 mL 0472-0404-92
Carton of 118 mL 0472-0404-94

Inactive ingredients: carbomer homopolymer type c, hypromelloses, mineral oil, peg-6 isostearate, polysorbate 80, propylene glycol, water, sodium hydroxide
FDA label
Alembic PharmaceuticalsShampoo 0.05% · Spray 5%

How it looks, what’s in it, NDCs

0.05%

Package NDC
Carton of 118 mL 62332-548-04

5%

Package NDC
Carton of 59 mL 62332-425-59
Carton of 125 mL 62332-425-12

Inactive ingredients: alcohol, citric acid monohydrate, coco-betaine, polyquaternium-10 (400 cps at 2%), water, sodium citrate, sodium laureth sulfate, isopropyl myristate, sodium lauryl sulfate, undecylenic acid
FDA label
Amneal PharmaceuticalsShampoo 0.05%

How it looks, what’s in it, NDCs

0.05% Colorless to pale yellow

Package NDC
Carton of 118 mL 69238-1732-8

Inactive ingredients: alcohol, citric acid monohydrate, coco-betaine, polyquaternium-10 (400 cps at 2%), water, sodium citrate, sodium laureth sulfate
FDA label
Lupin PharmaceuticalsLotion 0.05%

How it looks, what’s in it, NDCs

0.05% White to off white, opaque to translucent

Package NDC
Carton of 59 mL 68180-536-01
Carton of 118 mL 68180-536-02

Inactive ingredients: carbomer copolymer type b (allyl pentaerythritol crosslinked), hypromelloses, mineral oil, peg-6 isostearate, propylene glycol, water, sodium hydroxide
FDA label
NorthStar RxShampoo 0.05%

Made by Sun Pharma Canada

Product page on northstarrxllc.com

How it looks, what’s in it, NDCs

0.05% Pale yellow

Package NDC
Carton of 118 mL 16714-030-01

Inactive ingredients: alcohol, citric acid monohydrate, coco-betaine, polyquaternium-10 (400 mpa.s at 2%), monosodium citrate, sodium laureth-2 sulfate, water
FDA label
PadagisShampoo 0.05%

Product page on padagis.com

How it looks, what’s in it, NDCs

0.05%

Package NDC
Bottle of 118 mL 45802-961-26

Inactive ingredients: alcohol, hydrochloric acid, water, sodium laureth-3 sulfate, coco-betaine, polyquaternium-10 (400 mpa.s at 2%)
FDA label
Sun Pharmaceutical IndustriesShampoo 0.05% · Lotion 0.05% · Spray 5%

How it looks, what’s in it, NDCs

0.05% Pale yellow

Package NDC
Carton of 118 mL 51672-1347-8

0.05% Opaque

Package NDC
Carton of 59 mL 51672-1350-4
Carton of 118 mL 51672-1350-8

5%

Package NDC
Carton of 59 mL 51672-1371-4
Carton of 125 mL 51672-1371-8

Inactive ingredients: alcohol, citric acid monohydrate, coco-betaine, polyquaternium-10 (400 mpa.s at 2%), monosodium citrate, sodium laureth-2 sulfate, water, carbomer homopolymer type b (allyl sucrose crosslinked), dimethicone, isopropyl myristate, mineral oil, propylene glycol, sodium hydroxide, white wax, sodium lauryl sulfate, undecylenic acid
FDA label
Viona PharmaceuticalsLotion 0.05%

Made by Zydus Lifesciences

Product page on vionausa.com

How it looks, what’s in it, NDCs

0.05%

Package NDC
Carton of 59 mL 72578-085-01
Carton of 118 mL 72578-085-02

Inactive ingredients: cetostearyl alcohol, glyceryl monostearate, peg-100 stearate, glyceryl stearate/peg-100 stearate, mineral oil, peg-6 isostearate, propylene glycol, water
FDA label
Zydus LifesciencesSpray 5%

How it looks, what’s in it, NDCs

5%

Package NDC
Carton of 59 mL 68382-998-01
Carton of 125 mL 68382-998-02

Inactive ingredients: alcohol, isopropyl myristate, sodium lauryl sulfate, undecylenic acid

Package	NDC
Carton of 118 mL	43538-950-04

Package	NDC
Carton of 59 mL	0472-0404-92
Carton of 118 mL	0472-0404-94

Package	NDC
Carton of 118 mL	62332-548-04

Package	NDC
Carton of 59 mL	62332-425-59
Carton of 125 mL	62332-425-12

Package	NDC
Carton of 118 mL	69238-1732-8

Package	NDC
Carton of 59 mL	68180-536-01
Carton of 118 mL	68180-536-02

Package	NDC
Carton of 118 mL	16714-030-01

Package	NDC
Bottle of 118 mL	45802-961-26

Package	NDC
Carton of 118 mL	51672-1347-8

Package	NDC
Carton of 59 mL	51672-1350-4
Carton of 118 mL	51672-1350-8

Package	NDC
Carton of 59 mL	51672-1371-4
Carton of 125 mL	51672-1371-8

Package	NDC
Carton of 59 mL	72578-085-01
Carton of 118 mL	72578-085-02

Package	NDC
Carton of 59 mL	68382-998-01
Carton of 125 mL	68382-998-02

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

Scalp psoriasis

What the FDA label says

Clobetasol Propionate Shampoo, 0.05% is a corticosteroid indicated for the treatment of moderate to severe scalp psoriasis in subjects 18 years of age and older. Limitations of Use:

Do not use on the face, axillae or groin.
Avoid any contact with the eyes and lips.

Source: the FDA label for clobetasol propionate (Mayne Pharma Inc.), August 16, 2023. Full label on DailyMed

Good to know

It may look different from Clobex (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Cash prices can differ a lot from one pharmacy to the next, so it can pay to ask two. With insurance, what you pay depends on your plan.
If your pharmacy doesn’t stock it, they can often order it within a day or two.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/clobex/