Comtan vs. its authorized generic and generics

How to pay the least

Lowest price

$13.70 for 30 tablets delivered ($8.45 plus $5.25 shipping)

Generic entacapone 200 mg from Cost Plus Drugs, by mail

Make a free account on costplusdrugs.com. Ask your prescriber to send the prescription there, or Cost Plus Drugs can transfer it.Open Cost Plus Drugs
Order generic entacapone 200 mg. It comes by mail.

Need it today? $17.07 for 30 tablets with the free Team Cuban Card, at pharmacies that take it. Get the free card and show it there.

See the price and get the card

For 3 months at a time $25 for 90 tablets from Rx Outreach, by mail. Ask your prescriber to write it for 90 days.

Open Rx Outreach

A regular generic has the same active ingredient as Comtan, and the FDA requires it to work the same way.

Compare every option

Brand nameComtan

Authorized genericentacapone

Regular genericentacapone

What you’d pay

Not soldNo longer sold

Cash priceAsk the pharmacyUsually among the lowest

Cash price$13.70for 30 tablets at Cost Plus Drugs, with shipping

Same as Comtan?

–

Same medicine

Same active ingredientFillers and dyes can differ

Brand nameNot sold

Comtan itself isn’t sold as a prescription anymore. Its generic versions, if any, are in the other tabs.

See the authorized generic →

Authorized genericThe NDC to ask for

The same medicine as Comtan, without the brand name. Give the pharmacy its NDC to get it.

entacapone

Sold by (either works)

SandozMade by Orion, the company behind Comtan
Sun Pharmaceutical IndustriesMade by Orion, the company behind Comtan

NDC to ask for

200 mgtabletSandoz
- 0781-5578-0111-digit: 00781-5578-01100 tablets per bottle
200 mgtabletSun Pharmaceutical Industries
- 47335-007-8811-digit: 47335-0007-88100 tablets per bottle

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Comtan, can you tell me what I’d pay for the brand, for the authorized generic, and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

200 mg tablet · Sandoz

Comtan itself isn’t sold anymore, so there’s no current brand label to compare. Here’s the authorized generic’s label.

Authorized generic package label from Sandoz — Authorized genericSandoz

See the ingredients

Active: entacapone 200 mg

Inactive:

Croscarmellose sodium
Ferric oxide red
Ferric oxide yellow
Glycerin
Hydrogenated cottonseed oil
Hypromellose
Magnesium stearate
Mannitol
Microcrystalline cellulose
Polysorbate 80
Sucrose
Titanium dioxide

200 mg tablet · Sun Pharmaceutical Industries

Comtan itself isn’t sold anymore, so there’s no current brand label to compare. Here’s the authorized generic’s label.

Authorized generic package label from Sun Pharmaceutical Industries — Authorized genericSun Pharmaceutical Industries

See the ingredients

Active: entacapone 200 mg

Inactive:

Microcrystalline cellulose
Croscarmellose sodium
Ferric oxide red
Ferric oxide yellow
Glycerin
Hydrogenated cottonseed oil
Hypromelloses
Magnesium stearate
Mannitol
Polysorbate 80
Sucrose
Titanium dioxide

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic entacapone, lowest first.

Pick up in storeDelivered

Delivered: Cost Plus Drugs $8.45for 30 tablets200 mgPlus $5.25 shipping
Delivered: Rx Outreach $15for 30 tablets200 mg90 tablets: $25Free delivery
Pick up in store: Target (CVS) + Optum Perks $45.21for 90 tablets200 mgFree Optum Perks coupon · not with insuranceFind the nearest store
Pick up in store: Costco $63.99for 120 tablets200 mgMembers only · $65 a yearFind the nearest store
Delivered: Costco $63.99for 120 tablets200 mgMembers only · $65 a year · Plus shipping
Pick up in store: Team Cuban Card $17.07for 30 tablets200 mgFree card · Kroger, Albertsons, Safeway, Meijer and many local pharmaciesFind a pharmacy that takes it
Delivered: Amazon Pharmacy $27.20for 30 tablets200 mgPrime members only · $139 a year · Free delivery · Prime price: limits on some medicines if you're over 65 or have Medicare, Medicaid or TRICARE
Pick up in store: Walgreens + Optum Perks $91.67for 90 tablets200 mgFree Optum Perks coupon · not with insuranceFind the nearest store
Pick up in store: Sam's Club See its pricePlus members only · $120 a yearFind the nearest store

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericWho makes it

6 companies sell a generic of Comtan that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

Ajanta Pharma200 mg

Product page on ajantapharmausa.com

How it looks, what’s in it, NDCs

200 mg Light brown, oval, 18 mm, marked “EN1”

Package NDC
Bottle of 100 27241-049-10

Inactive ingredients: microcrystalline cellulose, sodium starch glycolate type a potato, hypromellose, polyoxyl 40 hydrogenated castor oil, water, magnesium stearate, polyethylene glycol, ferric oxide red, ferric oxide yellow, titanium dioxide, talc, polyvinyl alcohol
FDA label
Alembic Pharmaceuticals200 mg

How it looks, what’s in it, NDCs

200 mg Brownish-orange, oval, 17 mm, marked “L633”

Package NDC
Bottle of 100 62332-478-31
Bottle of 1000 62332-478-91

Inactive ingredients: microcrystalline cellulose, mannitol, croscarmellose sodium, silicon dioxide, magnesium stearate, hydrogenated cottonseed oil, hypromellose, glycerin, titanium dioxide, ferric oxide yellow, sucrose, polysorbate 80, ferric oxide red
FDA label
Aurobindo Pharma200 mg

Has lactose

Product page on aurobindousa.com

How it looks, what’s in it, NDCs

200 mg Light brownish orange, oval, 17 mm, marked “Y / 16”

Package NDC
Bottle of 100 65862-654-01
Bottle of 1000 65862-654-99

Inactive ingredients: croscarmellose sodium, glycerin, hydrogenated cottonseed oil, hypromellose 2910 (6 mpa.s), ferric oxide red, ferric oxide yellow, lactose monohydrate, magnesium stearate, mannitol, microcrystalline cellulose, polysorbate 80, sodium starch glycolate type a potato, sucrose, titanium dioxide
FDA label
Lannett200 mg

Made by Sunshine Lake

Product page on lannett.com

How it looks, what’s in it, NDCs

200 mg Orange, oval, 16 mm, marked “S51”

Package NDC
Bottle of 100 0527-1830-37

Inactive ingredients: microcrystalline cellulose, mannitol, sodium starch glycolate type b potato, povidone, magnesium stearate, polyvinyl alcohol, talc, polyethylene glycol 4000, lecithin, soybean, ferric oxide yellow, ferric oxide red, titanium dioxide
FDA label
Macleods Pharmaceuticals200 mg

How it looks, what’s in it, NDCs

200 mg Brown, oval, 17 mm, marked “L7”

Package NDC
Bottle of 100 33342-260-11
Bottle of 500 33342-260-15

Inactive ingredients: cellulose, microcrystalline, starch, corn, croscarmellose sodium, magnesium stearate, hypromelloses, titanium dioxide, propylene glycol, talc, ferric oxide yellow, ferric oxide red, povidone
FDA label
Rising Pharma Holdings200 mg

Made by Sunshine Lake

How it looks, what’s in it, NDCs

200 mg Orange, oval, 16 mm, marked “S51”

Package NDC
Bottle of 100 64980-722-01

Inactive ingredients: microcrystalline cellulose, mannitol, sodium starch glycolate type b potato, povidone, magnesium stearate, polyvinyl alcohol, talc, polyethylene glycol 4000, lecithin, soybean, ferric oxide yellow, ferric oxide red, titanium dioxide
FDA label

Package	NDC
Bottle of 100	27241-049-10

Package	NDC
Bottle of 100	62332-478-31
Bottle of 1000	62332-478-91

Package	NDC
Bottle of 100	65862-654-01
Bottle of 1000	65862-654-99

Package	NDC
Bottle of 100	0527-1830-37

Package	NDC
Bottle of 100	33342-260-11
Bottle of 500	33342-260-15

Package	NDC
Bottle of 100	64980-722-01

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

Parkinson’s symptoms that return as a dose wears off

What the FDA label says

Entacapone Tablets are indicated as an adjunct to levodopa and carbidopa to treat end-of-dose “wearing-off” in patients with Parkinson’s disease (see CLINICAL PHARMACOLOGY, Clinical Studies).

Entacapone Tablets’ effectiveness has not been systematically evaluated in patients with Parkinson’s disease who do not experience end-of-dose “wearing-off”.

Source: the FDA label for Entacapone (Sun Pharmaceutical Industries, Inc.), October 25, 2018. Full label on DailyMed

Good to know

It may look different from Comtan (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Cash prices can differ a lot from one pharmacy to the next, so it can pay to ask two. With insurance, what you pay depends on your plan.
If your pharmacy doesn’t stock it, they can often order it within a day or two.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/comtan/