An authorized generic of Cosmegen was sold before, but it isn’t sold now. Ask your pharmacist whether a regular generic (dactinomycin) is available.
Source: FDA, updated October 30, 2026
How to pay the least
Ask for the cash price
Generic dactinomycin
No pharmacy we check posts a price for it.
- Ask your pharmacy for the cash price of generic dactinomycin.Find pharmacies near you
- Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.
A regular generic has the same active ingredient as Cosmegen, and the FDA requires it to work the same way.
Compare every option
Question
Brand nameCosmegen
Authorized genericdactinomycin
Regular genericdactinomycin
What you’d pay
Not soldNo longer sold
Not soldNo longer sold
Cash priceAsk the pharmacy
Same as Cosmegen?
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Same active ingredientFillers and dyes can differ
Details for each option
Details for
Brand nameNot sold
Cosmegen itself isn’t sold as a prescription anymore. Its generic versions, if any, are in the other tabs.
Authorized genericNot sold now
Regular genericWho makes it
4 companies sell a generic of Cosmegen that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.
It’s mostly filled by specialty pharmacies. Your prescriber’s office or insurer can tell you which one to use.
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Eugia0.5 mg/mL
How it looks, what’s in it, NDCs
0.5 mg/mL
Package NDC Carton of 1 mL 55150-431-01 0.5 mg/mL
Package NDC Carton of 1 mL 55150-928-02 Inactive ingredients: mannitol
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Hisun Pharmaceuticals0.5 mg
How it looks, what’s in it, NDCs
0.5 mg
Package NDC Carton of 1 42658-008-01 Inactive ingredients: mannitol
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Meitheal Pharmaceuticals0.5 mg/mL
Product page on meithealpharma.com
How it looks, what’s in it, NDCs
0.5 mg/mL
Package NDC Carton of 1 mL 71288-129-02 Inactive ingredients: mannitol, water
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XGen Pharmaceuticals DJB0.5 mg/mL
Product page on xgenpharmadjb.com
How it looks, what’s in it, NDCs
0.5 mg/mL
Package NDC Carton of 1 mL 39822-2100-2 Inactive ingredients: mannitol
Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.
What it’s used for
- Wilms tumor (a kidney cancer)
- Rhabdomyosarcoma (a soft-tissue cancer)
- Ewing sarcoma
- Testicular cancer that has spread
- Gestational trophoblastic neoplasia (a pregnancy tumor)
- Solid tumors in one area, including ones that came back
What the FDA label says
Wilms Tumor
COSMEGEN is indicated for the treatment of adult and pediatric patients with Wilms tumor, as part of a multi-phase, combination chemotherapy regimen.
Rhabdomyosarcoma
COSMEGEN is indicated for the treatment of adult and pediatric patients with rhabdomyosarcoma, as part of a multi-phase, combination chemotherapy regimen.
Ewing Sarcoma
COSMEGEN is indicated for the treatment of adult and pediatric patients with Ewing sarcoma, as part of a multi-phase, combination chemotherapy regimen.
Metastatic Nonseminomatous Testicular Cancer
COSMEGEN is indicated for the treatment of adult and pediatric patients with metastatic, nonseminomatous testicular cancer, as part of a multi-phase, combination chemotherapy regimen.
Gestational Trophoblastic Neoplasia
COSMEGEN is indicated for the treatment of post-menarchal patients with gestational trophoblastic neoplasia, as a single agent or as part of a combination chemotherapy regimen.
Regional Perfusion in Locally Recurrent and Locoregional Solid Malignancies
COSMEGEN is indicated for the treatment of adult patients with locally recurrent or locoregional solid malignancies, as a component of palliative or adjunctive regional perfusion.
Source: the FDA label for Cosmegen (Recordati Rare), August 15, 2018. Full label from the FDA (PDF)
Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/cosmegen/