Cosopt vs. generic dorzolamide and timolol: side by side

How to pay the least

Ask for the cash price

Generic dorzolamide and timolol

No pharmacy we check posts a price for it.

Ask your pharmacy for the cash price of generic dorzolamide and timolol.Find pharmacies near you
Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Cosopt, and the FDA requires it to work the same way.

Compare every option

Brand nameCosopt

Authorized genericdorzolamide and timolol

Regular genericdorzolamide and timolol

What you’d pay

Cash priceAsk the pharmacyUsually the highest price

Not soldThere isn’t one

Cash priceAsk the pharmacyUsually the lowest

Same as Cosopt?

The original

–

Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Cosopt’s maker. Ask the pharmacy for Cosopt’s cash price. With insurance, ask what your plan charges.

Authorized genericNot sold

There isn’t one. An authorized generic is Cosopt itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.

See the regular generic →

Regular genericWho makes it

8 companies sell a generic of Cosopt that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

Alembic Pharmaceuticals2% / 0.5%

How it looks, what’s in it, NDCs

2% / 0.5%

Package NDC
Carton of 10 mL 62332-553-10

Inactive ingredients: benzalkonium chloride, hydroxyethyl cellulose (2000 mpa.s at 1%), mannitol, trisodium citrate dihydrate, sodium hydroxide, water
FDA label
Aurobindo Pharma2% / 0.5%

Made by Eugia Pharma Specialities

Product page on aurobindousa.com

How it looks, what’s in it, NDCs

2% / 0.5%

Package NDC
Carton of 10 mL 65862-946-01

Inactive ingredients: hydroxyethyl cellulose (4000 mpa.s at 1%), mannitol, trisodium citrate dihydrate, sodium hydroxide, water, benzalkonium chloride
FDA label
Bausch & Lomb2% / 0.5%

How it looks, what’s in it, NDCs

2% / 0.5%

Package NDC
Carton of 5 mL 24208-486-05
Carton of 10 mL 24208-486-10

Inactive ingredients: benzalkonium chloride, hydroxyethyl cellulose (2000 mpa.s at 1%), mannitol, water, trisodium citrate dihydrate, sodium hydroxide
FDA label
Florida Pharmaceutical Products2% / 0.5%

Made by Regcon Holdings

Product page on flpharmaproducts.com

How it looks, what’s in it, NDCs

2% / 0.5%

Package NDC
Carton of 10 mL 71921-226-10

Inactive ingredients: mannitol, sodium citrate, sodium hydroxide, benzalkonium chloride, hydroxyethyl cellulose (2000 mpa.s at 1%), hydroxyethyl cellulose (4000 mpa.s at 1%), water
FDA label
Leading Pharma2% / 0.5%

Made by FDC

How it looks, what’s in it, NDCs

2% / 0.5%

Package NDC
Carton of 5 mL 69315-305-05
Carton of 10 mL 69315-305-10

Inactive ingredients: hydroxyethyl cellulose (2000 mpa.s at 1%), hydroxyethyl cellulose (4000 mpa.s at 1%), mannitol, sodium citrate, benzalkonium chloride, sodium hydroxide, water
FDA label
Micro Labs2.23% / 0.68%

Product page on microlabsusa.com

How it looks, what’s in it, NDCs

2.23% / 0.68% Colorless to nearly colorless

Package NDC
Carton of 10 mL 42571-147-26

Inactive ingredients: mannitol, hydroxyethyl cellulose (4000 mpa.s at 1%), sodium hydroxide, trisodium citrate dihydrate, water, benzalkonium chloride
FDA label
Sandoz2% / 0.5%

How it looks, what’s in it, NDCs

2% / 0.5%

Package NDC
Bottle of 5 mL 61314-030-01
Bottle of 10 mL 61314-030-02

Inactive ingredients: sodium citrate form, hydroxyethyl cellulose (2000 mpa.s at 1%), sodium hydroxide, mannitol, water, benzalkonium chloride
Somerset Therapeutics2% / 0.5%

Product page on somersetpharma.com

How it looks, what’s in it, NDCs

2% / 0.5% A clear, colorless to nearly colorless solution

Package NDC
Carton of 10 mL 70069-051-01

Inactive ingredients: benzalkonium chloride, trisodium citrate dihydrate, mannitol, hydroxyethyl cellulose (2000 mpa.s at 1%), sodium hydroxide, water
FDA label

Package	NDC
Carton of 10 mL	62332-553-10

Package	NDC
Carton of 10 mL	65862-946-01

Package	NDC
Carton of 5 mL	24208-486-05
Carton of 10 mL	24208-486-10

Package	NDC
Carton of 10 mL	71921-226-10

Package	NDC
Carton of 5 mL	69315-305-05
Carton of 10 mL	69315-305-10

Package	NDC
Carton of 10 mL	42571-147-26

Package	NDC
Bottle of 5 mL	61314-030-01
Bottle of 10 mL	61314-030-02

Package	NDC
Carton of 10 mL	70069-051-01

The FDA doesn’t rate Ingenus Pharmaceuticals’s version of dorzolamide and timolol a substitute for Cosopt, so a pharmacy can’t swap it in without your prescriber’s OK.

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What to say at the pharmacy

“Before you fill my Cosopt, can you tell me what I’d pay for the brand and for a generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

What it’s used for

Glaucoma and high eye pressure

What the FDA label says

COSOPT is a combination of dorzolamide hydrochloride, a carbonic anhydrase inhibitor, and timolol maleate, a beta-adrenergic receptor blocking agent, indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers.
The IOP-lowering of COSOPT twice daily was slightly less than that seen with the concomitant administration of 0.5% timolol twice daily, and 2% dorzolamide three times daily.

Source: the FDA label for Cosopt (Thea Pharma Inc.), April 17, 2024. Full label on DailyMed

Good to know

A regular generic may look different from Cosopt. The FDA requires it to work the same way.
We didn’t find a savings card from Cosopt’s maker.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/cosopt/