Cystadane savings card: $0 a fill with commercial insurance

How to pay the least

Ask for the cash price

Generic betaine

No pharmacy we check posts a price for it.

Ask your pharmacy for the cash price of generic betaine.Find pharmacies near you
Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Cystadane, and the FDA requires it to work the same way.

Compare every option

Brand nameCystadane

Authorized genericbetaine

Regular genericbetaine

What you’d pay

Cash priceAsk the pharmacyUsually the highest price

Not soldThere isn’t one

Cash priceAsk the pharmacyUsually the lowest

Same as Cystadane?

The original

–

Same active ingredientFillers and dyes can differ

Brand nameThe maker’s card

Recordati Rare Diseases Copay Assistance Program

Savings card from Recordati Rare Diseases

No insuranceNeeds insuranceNo cash price listed.

Insurance $0 a fill

Or call 1-888-487-4703.

In the maker’s words

“Recordati Rare Diseases, the distributor of CYSTADANE, is offering a $0 copay for qualified patients with commercial insurance.”

From the maker’s offer on cystadane.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Cystadane itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.

See the regular generic →

Regular genericMakers and their savings cards

2 companies sell a generic of Cystadane that the FDA rates a substitute. A pharmacy fills whichever one it stocks. One of them has its own savings card, listed first. It works only with that maker’s version. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

It’s mostly filled by specialty pharmacies. Your prescriber’s office or insurer can tell you which one to use.

Eton Pharmaceuticals100%

Eton Cares (Betaine Anhydrous)

With commercial insurance as little as $0

Sign up on betaineus.com

In the maker’s words
“Eton Cares can help eligible, commercially insured patients get their medication for as little as $0 per month.”

Packages and NDCs

100% White

Package NDC
Bottle of 180 g 71863-115-18

FDA label
Cosette Pharmaceuticals100%

Made by Novitium Pharma

Product page on cosettepharma.com

Packages and NDCs

100% White to off-white

Package NDC
Bottle of 180 g 0713-0352-81

FDA label

Package	NDC
Bottle of 180 g	71863-115-18

Package	NDC
Bottle of 180 g	0713-0352-81

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

What to say at the pharmacy

“Before you fill my Cystadane, can you tell me what I’d pay for the brand and for a generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

What it’s used for

Homocystinuria (high homocysteine in the blood)

What the FDA label says

CYSTADANE is a methylating agent indicated in pediatric and adult patients for the treatment of homocystinuria to decrease elevated homocysteine blood concentrations. Included within the category of homocystinuria are:

Cystathionine beta-synthase (CBS) deficiency
5,10-methylenetetrahydrofolate reductase (MTHFR) deficiency
Cobalamin cofactor metabolism (cbl) defect

Source: the FDA label for Cystadane (Recordati Rare Diseases), April 24, 2026. Full label on DailyMed

Good to know

A regular generic may look different from Cystadane. The FDA requires it to work the same way.
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/cystadane/