Depo-Provera vs. its authorized generic and generics

How to pay the least

Ask for the cash price

Generic medroxyprogesterone

No pharmacy we check posts a price for it.

Ask your pharmacy for the cash price of generic medroxyprogesterone.Find pharmacies near you
Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Depo-Provera, and the FDA requires it to work the same way.

Compare every option

Brand nameDepo-Provera

Authorized genericmedroxyprogesterone

Regular genericmedroxyprogesterone

What you’d pay

Cash priceAsk the pharmacyUsually the highest price

Cash priceAsk the pharmacyUsually among the lowest

Same as Depo-Provera?

The original

Same medicine

Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Depo-Provera’s maker. Ask the pharmacy for Depo-Provera’s cash price. With insurance, ask what your plan charges.

Authorized genericThe NDC to ask for

The same medicine as Depo-Provera, without the brand name. Give the pharmacy its NDC to get it.

medroxyprogesterone

Sold by

Prasco Laboratories

NDC to ask for

150 mg/mLinjectable suspension
- 66993-370-2511-digit: 66993-0370-2525 vials, 1 mL each
- 66993-370-8311-digit: 66993-0370-831 mL per vial
150 mg/mLinjectable suspension
- 66993-371-7911-digit: 66993-0371-791 mL per syringe

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Depo-Provera, can you tell me what I’d pay for the brand, for the authorized generic from Prasco Laboratories (NDC 66993-370-25), and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

Same active and inactive ingredients as Depo-Provera.

Depo-Provera package label — BrandDepo-Provera

Authorized generic package label from Prasco Laboratories — Authorized genericPrasco Laboratories

See the ingredients

Active: medroxyprogesterone acetate 150 mg/mL

Inactive, on both labels:

Hydrochloric acid
Methylparaben
Polyethylene glycol 3350
Polysorbate 80
Propylparaben
Sodium chloride
Sodium hydroxide
Water

Regular genericWho makes it

4 companies sell a generic of Depo-Provera that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

Amneal PharmaceuticalsSuspension 150 mg/mL

Made by Xiromed

How it looks, what’s in it, NDCs

150 mg/mL

Package NDC
Carton of 1 mL 60219-1467-1
Carton of 25 mL 60219-1467-2

150 mg/mL

Package NDC
Carton of 1 mL 70121-1467-2
Carton of 25 mL 70121-1467-5

150 mg/mL

Package NDC
Carton of 1 mL 70121-1480-1

Inactive ingredients: polyethylene glycol 3350, polysorbate 80, sodium chloride, methylparaben, propylparaben, water, sodium hydroxide, hydrochloric acid
FDA label
Amphastar PharmaceuticalsER suspension 150 mg/mL

How it looks, what’s in it, NDCs

150 mg/mL

Package NDC
Carton of 1 mL 0548-5400-00
Carton of 25 mL 0548-5400-25

150 mg/mL

Package NDC
Carton of 1 mL 0548-5701-00

Inactive ingredients: polyethylene glycol 3350, polysorbate 80, sodium chloride, methylparaben, propylparaben, water, sodium hydroxide, hydrochloric acid
FDA label
EugiaSuspension 150 mg/mL

Product page on eugiaus.com

How it looks, what’s in it, NDCs

150 mg/mL

Package NDC
Carton of 1 mL 55150-329-01
Carton of 25 mL 55150-329-25

150 mg/mL

Package NDC
Carton of 1 mL 55150-330-01

Inactive ingredients: polyethylene glycol 3350, polysorbate 80, sodium chloride, methylparaben, propylparaben, water, sodium hydroxide, hydrochloric acid
FDA label
XiromedSuspension 150 mg/mL

Product page on xiromed.com

How it looks, what’s in it, NDCs

150 mg/mL

Package NDC
Carton of 1 mL 70700-315-27
Carton of 25 mL 70700-315-25

Inactive ingredients: polyethylene glycol 3350, polysorbate 80, sodium chloride, methylparaben, propylparaben, water, sodium hydroxide, hydrochloric acid
FDA label

Package	NDC
Carton of 1 mL	60219-1467-1
Carton of 25 mL	60219-1467-2

Package	NDC
Carton of 1 mL	70121-1467-2
Carton of 25 mL	70121-1467-5

Package	NDC
Carton of 1 mL	70121-1480-1

Package	NDC
Carton of 1 mL	0548-5400-00
Carton of 25 mL	0548-5400-25

Package	NDC
Carton of 1 mL	0548-5701-00

Package	NDC
Carton of 1 mL	55150-329-01
Carton of 25 mL	55150-329-25

Package	NDC
Carton of 1 mL	55150-330-01

Package	NDC
Carton of 1 mL	70700-315-27
Carton of 25 mL	70700-315-25

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

Preventing pregnancy (birth control)

What the FDA label says

Depo-Provera CI is a progestin indicated for use by females of reproductive potential to prevent pregnancy.

Limitations of Use:

The use of Depo-Provera CI is not recommended as a long-term (i.e., longer than 2 years) birth control method unless other options are considered inadequate.

Source: the FDA label for Depo-Provera (Pharmacia & Upjohn Company LLC), August 25, 2026. Full label on DailyMed

Good to know

It may look different from Depo-Provera (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Cash prices can differ a lot from one pharmacy to the next, so it can pay to ask two. With insurance, what you pay depends on your plan.
If your pharmacy doesn’t stock it, they can often order it within a day or two.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/depo-provera/