An authorized generic of Derma-Smoothe/FS was sold before, but it isn’t sold now. Ask your pharmacist whether a regular generic (fluocinolone acetonide) is available.
Source: FDA, updated October 30, 2026
Generic name: fluocinolone acetonide
Used for: Scalp psoriasis
Ask for the cash price
Generic fluocinolone acetonide
No pharmacy we check posts a price for it.
A regular generic has the same active ingredient as Derma-Smoothe/FS, and the FDA requires it to work the same way.
Details for each option
We didn’t find a savings card or cash price from Derma-Smoothe/FS’s maker. Ask the pharmacy for Derma-Smoothe/FS’s cash price. With insurance, ask what your plan charges.
An authorized generic of Derma-Smoothe/FS was sold before, but it isn’t sold now. Ask your pharmacist whether a regular generic (fluocinolone acetonide) is available.
Source: FDA, updated October 30, 2026
4 companies sell a generic of Derma-Smoothe/FS that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.
0.01 mg/100 mL TO PALE YELLOW
| Package | NDC |
|---|---|
| Carton of 118.28 mL | 45802-485-26 |
0.01 mg/100 mL PALE YELLOW
| Package | NDC |
|---|---|
| Bottle of 118.28 mL | 45802-887-26 |
Inactive ingredients: isopropyl alcohol, isopropyl myristate, light mineral oil, oleth-2
0.011%
| Package | NDC |
|---|---|
| Carton of 118.28 mL | 70752-156-06 |
0.011%
| Package | NDC |
|---|---|
| Carton of 118.28 mL | 70752-158-06 |
Sold as Fluocinolone Acetonide Oil
0.011%
| Package | NDC |
|---|---|
| Bottle of 118.28 mL | 64980-330-04 |
0.011%
| Package | NDC |
|---|---|
| Bottle of 118.28 mL | 64980-331-04 |
Inactive ingredients: isopropyl alcohol, isopropyl myristate, light mineral oil, oleth-2, peanut oil
0.11 mg/118.28 mL Clear or translucent, colorless to yellow liquid
| Package | NDC |
|---|---|
| Carton of 118.28 mL | 51672-1356-8 |
0.11 mg/118.28 mL (Clear or translucent, colorless to yellow)
| Package | NDC |
|---|---|
| Carton of 118.28 mL | 51672-1357-8 |
Inactive ingredients: isopropyl alcohol, isopropyl myristate, light mineral oil, oleth-2, peanut oil
Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.
Derma-Smoothe/FS ® Scalp Oil is a corticosteroid indicated for the treatment of psoriasis of the scalp in adults.
Source: the FDA label for Derma-Smoothe/FS (Royal Pharmaceuticals), June 9, 2026. Full label on DailyMed
Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/derma-smoothe-fs/