Diprolene vs. its authorized generic and generics

How to pay the least

Ask for the cash price

Generic betamethasone dipropionate

No pharmacy we check posts a price for it.

Ask your pharmacy for the cash price of generic betamethasone dipropionate.Find pharmacies near you
Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Diprolene, and the FDA requires it to work the same way.

Compare every option

Brand nameDiprolene

Authorized genericbetamethasone dipropionate

Regular genericbetamethasone dipropionate

What you’d pay

Cash priceAsk the pharmacyUsually the highest price

Cash priceAsk the pharmacyOften less than Diprolene

Cash priceAsk the pharmacyUsually the lowest

Same as Diprolene?

The original

Same medicine

Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Diprolene’s maker. Ask the pharmacy for Diprolene’s cash price. With insurance, ask what your plan charges.

Authorized genericThe NDC to ask for

The same medicine as Diprolene, without the brand name. Give the pharmacy its NDC to get it.

betamethasone dipropionate

Sold by

Prasco LaboratoriesPart of Organon, the company behind Diprolene

NDC to ask for

0.05%ointment
- 66993-897-1511-digit: 66993-0897-1515 g per tube
- 66993-897-4911-digit: 66993-0897-4950 g per tube

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Diprolene, can you tell me what I’d pay for the brand, for the authorized generic from Prasco Laboratories (NDC 66993-897-15), and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

Same active and inactive ingredients as Diprolene.

Diprolene package label — BrandDiprolene

Authorized generic package label from Prasco Laboratories — Authorized genericPrasco Laboratories

See the ingredients

Active: betamethasone dipropionate 0.05%

Inactive, on both labels:

Petrolatum
Propylene glycol
Propylene glycol monopalmitostearate
White wax

Regular genericWho makes it

6 companies sell a generic of Diprolene that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

Actavis PharmaOintment 0.05%

How it looks, what’s in it, NDCs

0.05%

Package NDC
Carton of 15 g 0472-0382-15
Carton of 45 g 0472-0382-45

Inactive ingredients: propylene glycol, propylene glycol stearate, petrolatum, white wax
Burel PharmaceuticalsOintment 0.05%

Made by Aurobindo Pharma

How it looks, what’s in it, NDCs

0.05% White to off-white

Package NDC
Carton of 15 g 35573-107-15
Carton of 50 g 35573-107-49

Inactive ingredients: propylene glycol, propylene glycol monopalmitostearate, white petrolatum, white wax
FDA label
Encube EthicalsLotion 0.05%

How it looks, what’s in it, NDCs

0.05%

Package NDC
Carton of 30 mL 21922-104-21
Carton of 60 mL 21922-104-01

Inactive ingredients: isopropyl alcohol, hydroxypropyl cellulose (1600000 wamw), propylene glycol, sodium phosphate, monobasic, monohydrate, phosphoric acid, water
FDA label
Fougera PharmaceuticalsLotion 0.05% · Ointment 0.05%

How it looks, what’s in it, NDCs

0.05%

Package NDC
Bottle of 30 mL 0168-0267-30
Bottle of 60 mL 0168-0267-60

0.05%

Package NDC
Tube of 15 g 0168-0268-15
Tube of 50 g 0168-0268-50

Inactive ingredients: isopropyl alcohol, propylene glycol, water, hydroxypropyl cellulose (1600000 wamw), phosphoric acid, sodium phosphate, monobasic form, propylene glycol monostearate, white wax, petrolatum
FDA label
Lupin PharmaceuticalsOintment 0.05%

How it looks, what’s in it, NDCs

0.05% White to off-white opaque

Package NDC
Carton of 15 g 68180-947-01
Carton of 50 g 68180-947-02

Inactive ingredients: petrolatum, propylene glycol, propylene glycol monopalmitostearate, white wax
FDA label
Sun Pharmaceutical IndustriesGel 0.05% · Lotion 0.05%

How it looks, what’s in it, NDCs

0.05%

Package NDC
Carton of 15 g 51672-1309-1
Carton of 50 g 51672-1309-3

0.05%

Package NDC
Carton of 30 mL 51672-1340-3
Carton of 60 mL 51672-1340-4

Inactive ingredients: carbomer homopolymer type c (allyl pentaerythritol crosslinked), propylene glycol, water, sodium hydroxide, hydroxypropyl cellulose (1600000 wamw), isopropyl alcohol, phosphoric acid, sodium phosphate, monobasic, monohydrate
FDA label

Package	NDC
Carton of 15 g	0472-0382-15
Carton of 45 g	0472-0382-45

Package	NDC
Carton of 15 g	35573-107-15
Carton of 50 g	35573-107-49

Package	NDC
Carton of 30 mL	21922-104-21
Carton of 60 mL	21922-104-01

Package	NDC
Bottle of 30 mL	0168-0267-30
Bottle of 60 mL	0168-0267-60

Package	NDC
Tube of 15 g	0168-0268-15
Tube of 50 g	0168-0268-50

Package	NDC
Carton of 15 g	68180-947-01
Carton of 50 g	68180-947-02

Package	NDC
Carton of 15 g	51672-1309-1
Carton of 50 g	51672-1309-3

Package	NDC
Carton of 30 mL	51672-1340-3
Carton of 60 mL	51672-1340-4

The FDA doesn’t rate Padagis’s version of betamethasone dipropionate a substitute for Diprolene, so a pharmacy can’t swap it in without your prescriber’s OK.

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

Itchy, inflamed skin conditions

What the FDA label says

DIPROLENE Ointment is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses in patients 13 years of age and older.

Source: the FDA label for Diprolene (Organon LLC), November 19, 2025. Full label on DailyMed

Good to know

It may look different from Diprolene (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Cash prices can differ a lot from one pharmacy to the next, so it can pay to ask two. With insurance, what you pay depends on your plan.
If your pharmacy doesn’t stock it, they can often order it within a day or two.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/diprolene/