Divigel

Generic name: estradiol

Used for: Hot flashes from menopause

How do you pay?

How to pay the least

Ask for the cash price

Generic estradiol

No pharmacy we check posts a price for it.

  1. Ask your pharmacy for the cash price of generic estradiol.Find pharmacies near you 
  2. Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Divigel, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameDivigel
Authorized genericestradiol
Regular genericestradiol
What you’d pay
Cash priceAsk the pharmacyUsually the highest price
Cash priceAsk the pharmacyUsually among the lowest
Cash priceAsk the pharmacyUsually among the lowest
Same as Divigel?
The original
Same medicine
Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Divigel’s maker. Ask the pharmacy for Divigel’s cash price. With insurance, ask what your plan charges.

Authorized genericThe NDC to ask for

The same medicine as Divigel, without the brand name. Give the pharmacy its NDC to get it.

estradiol

Sold by
  • Trigen LaboratoriesMade by Orion, which also makes Divigel
Your strength
NDC to ask for
  • 0.1%gel
    • 13811-093-3211-digit: 13811-0093-3230 packets, 1 g each
    • 13811-093-9211-digit: 13811-0093-9290 packets, 1 g each
  • 0.25 mg/0.25 ggel
    • 13811-090-3211-digit: 13811-0090-3230 packets, 0.25 g each
    • 13811-090-9211-digit: 13811-0090-9290 packets, 0.25 g each
  • 0.5 mg/0.5 ggel
    • 13811-091-3211-digit: 13811-0091-3230 packets, 0.5 g each
    • 13811-091-9211-digit: 13811-0091-9290 packets, 0.5 g each
  • 0.75 mg/0.75 ggel
    • 13811-092-3211-digit: 13811-0092-3230 packets, 0.75 g each
    • 13811-092-9211-digit: 13811-0092-9290 packets, 0.75 g each
  • 1.25 mg/1.25 ggel
    • 13811-094-3211-digit: 13811-0094-3230 packets, 1.25 g each
    • 13811-094-9211-digit: 13811-0094-9290 packets, 1.25 g each

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Divigel, can you tell me what I’d pay for the brand, for the authorized generic from Trigen Laboratories, and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

0.25 mg/0.25 g gel

Divigel doesn’t come in this strength, so there’s no brand label to compare.

Authorized genericTrigen Laboratories
See the ingredients

Active: estradiol 0.25 mg/0.25 g

Inactive:

  • Alcohol
  • Carbomer homopolymer type B
  • Carbomer homopolymer type C
  • Propylene glycol
  • Trolamine
  • Water

0.5 mg/0.5 g gel

Divigel doesn’t come in this strength, so there’s no brand label to compare.

Authorized genericTrigen Laboratories
See the ingredients

Active: estradiol 0.5 mg/0.5 g

Inactive:

  • Alcohol
  • Carbomer homopolymer type B
  • Carbomer homopolymer type C
  • Propylene glycol
  • Trolamine
  • Water

0.75 mg/0.75 g gel

Divigel doesn’t come in this strength, so there’s no brand label to compare.

Authorized genericTrigen Laboratories
See the ingredients

Active: estradiol 0.75 mg/0.75 g

Inactive:

  • Alcohol
  • Carbomer homopolymer type B
  • Carbomer homopolymer type C
  • Propylene glycol
  • Trolamine
  • Water

0.1% gel

Same active and inactive ingredients as Divigel.

BrandDivigel
Authorized genericTrigen Laboratories
See the ingredients

Active: estradiol 0.1%

Inactive, on both labels:

  • Alcohol
  • Carbomer homopolymer type B
  • Carbomer homopolymer type C
  • Propylene glycol
  • Trolamine
  • Water

1.25 mg/1.25 g gel

Same active and inactive ingredients as Divigel.

BrandDivigel
Authorized genericTrigen Laboratories
See the ingredients

Active: estradiol 1.25 mg/1.25 g

Inactive, on both labels:

  • Alcohol
  • Carbomer homopolymer type B
  • Carbomer homopolymer type C
  • Propylene glycol
  • Trolamine
  • Water

Regular genericWho makes it

6 companies sell a generic of Divigel that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • Amneal PharmaceuticalsAll 5 strengths
    How it looks, what’s in it, NDCs

    0.1% Clear, colorless

    PackageNDC
    Carton of 30 g69238-2449-3

    0.25 mg/0.25 g Clear, colorless

    PackageNDC
    Carton of 7.5 g69238-2452-3

    0.5 mg/0.5 g Clear, colorless

    PackageNDC
    Carton of 15 g69238-2451-3

    0.75 mg/0.75 g Clear, colorless

    PackageNDC
    Carton of 22.5 g69238-2450-3

    1.25 mg/1.25 g Clear, colorless

    PackageNDC
    Carton of 37.5 g69238-2448-3

    Inactive ingredients: carbomer homopolymer type b (allyl pentaerythritol crosslinked), alcohol, propylene glycol, water, trolamine

    FDA label

  • ANI PharmaceuticalsAll 5 strengths

    Made by Novitium Pharma

    Product page on anipharmaceuticals.com

    How it looks, what’s in it, NDCs

    0.1%

    PackageNDC
    Carton of 30 g70954-533-20

    0.25 mg/0.25 g

    PackageNDC
    Carton of 7.5 g70954-531-20

    0.5 mg/0.5 g

    PackageNDC
    Carton of 15 g70954-530-20

    0.75 mg/0.75 g

    PackageNDC
    Carton of 22.5 g70954-532-20

    1.25 mg/1.25 g

    PackageNDC
    Carton of 37.5 g70954-534-20

    Inactive ingredients: carbomer homopolymer type c (allyl pentaerythritol crosslinked), alcohol, propylene glycol, water, trolamine

    FDA label

  • Encube EthicalsAll 5 strengths
    How it looks, what’s in it, NDCs

    0.1%

    PackageNDC
    Carton of 30 g21922-089-52

    0.25 mg/0.25 g

    PackageNDC
    Carton of 7.5 g21922-086-52

    0.5 mg/0.5 g

    PackageNDC
    Carton of 15 g21922-087-52

    0.75 mg/0.75 g

    PackageNDC
    Carton of 22.5 g21922-088-52

    1.25 mg/1.25 g

    PackageNDC
    Carton of 37.5 g21922-090-52

    Inactive ingredients: propylene glycol, trolamine, water, alcohol, carbomer homopolymer type b

    FDA label

  • NorthStar RxAll 5 strengths

    Made by Novitium Pharma

    Product page on northstarrxllc.com

    How it looks, what’s in it, NDCs

    0.1%

    PackageNDC
    Carton of 30 g72603-244-30

    0.25 mg/0.25 g

    PackageNDC
    Carton of 7.5 g72603-241-30

    0.5 mg/0.5 g

    PackageNDC
    Carton of 15 g72603-242-30

    0.75 mg/0.75 g

    PackageNDC
    Carton of 22.5 g72603-243-30

    1.25 mg/1.25 g

    PackageNDC
    Carton of 37.5 g72603-245-30

    Inactive ingredients: carbomer homopolymer type c (allyl pentaerythritol crosslinked), alcohol, propylene glycol, water, trolamine

    FDA label

  • PadagisAll 5 strengths

    Product page on padagis.com

    How it looks, what’s in it, NDCs

    0.1%

    PackageNDC
    Carton of 30 g45802-452-30

    0.25 mg/0.25 g

    PackageNDC
    Carton of 7.5 g45802-134-30

    0.5 mg/0.5 g

    PackageNDC
    Carton of 15 g45802-202-30

    0.75 mg/0.75 g

    PackageNDC
    Carton of 22.5 g45802-310-30

    1.25 mg/1.25 g

    PackageNDC
    Carton of 37.5 g45802-573-30

    Inactive ingredients: carbomer homopolymer type c (allyl pentaerythritol crosslinked), alcohol, propylene glycol, trolamine, water

    FDA label

  • XiromedAll 5 strengths

    Product page on xiromed.com

    How it looks, what’s in it, NDCs

    0.1%

    PackageNDC
    Carton of 30 g70700-145-35

    0.25 mg/0.25 g

    PackageNDC
    Carton of 7.5 g70700-143-35

    0.5 mg/0.5 g

    PackageNDC
    Carton of 15 g70700-144-35

    0.75 mg/0.75 g

    PackageNDC
    Carton of 22.5 g70700-194-35

    1.25 mg/1.25 g

    PackageNDC
    Carton of 37.5 g70700-195-35

    Inactive ingredients: carbomer homopolymer type b (allyl pentaerythritol or allyl sucrose crosslinked), alcohol, propylene glycol, water, trolamine

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

What the FDA label says

Divigel is an estrogen indicated for the treatment of moderate to severe vasomotor symptoms due to menopause.

Source: the FDA label for Divigel (Vertical Pharmaceuticals, LLC), February 27, 2026. Full label on DailyMed 

Good to know

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/divigel/