Durezol vs. its authorized generic and generics

How to pay the least

Ask for the cash price

Generic difluprednate

No pharmacy we check posts a price for it.

Ask your pharmacy for the cash price of generic difluprednate.Find pharmacies near you
Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as Durezol, and the FDA requires it to work the same way.

Compare every option

Brand nameDurezol

Authorized genericdifluprednate

Regular genericdifluprednate

What you’d pay

Cash priceAsk the pharmacyUsually the highest price

Cash priceAsk the pharmacyUsually among the lowest

Same as Durezol?

The original

Same medicine

Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Durezol’s maker. Ask the pharmacy for Durezol’s cash price. With insurance, ask what your plan charges.

Authorized genericThe NDC to ask for

The same medicine as Durezol, without the brand name. Give the pharmacy its NDC to get it.

difluprednate

Sold by

SandozThe company behind Durezol

NDC to ask for

0.05%emulsion
- 0781-6000-7811-digit: 00781-6000-785 mL per bottle

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Durezol, can you tell me what I’d pay for the brand, for the authorized generic from Sandoz (NDC 0781-6000-78), and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

Same active and inactive ingredients as Durezol.

Authorized generic package label from Sandoz — Authorized genericSandoz

See the ingredients

Active: difluprednate 0.05%

Inactive, on both labels:

Boric acid
Castor oil
Edetate disodium
Glycerin
Polysorbate 80
Sodium acetate
Sodium hydroxide
Sorbic acid
Water

Regular genericWho makes it

6 companies sell a generic of Durezol that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

Amneal Pharmaceuticals0.05%

Packages and NDCs

0.05%

Package NDC
Carton of 5 mL 69238-1380-3
Caplin Steriles0.05%

Product page on caplin-us.com

How it looks, what’s in it, NDCs

0.05%

Package NDC
Carton of 5 mL 65145-161-01

Inactive ingredients: boric acid, castor oil, glycerin, polysorbate 80, water, sodium acetate, sodium hydroxide, edetate disodium, sorbic acid
FDA label
Dr. Reddy’s Laboratories0.05%

How it looks, what’s in it, NDCs

0.05%

Package NDC
Carton of 5 mL 43598-588-11

Inactive ingredients: boric acid, castor oil, glycerin, polysorbate 80, water, sodium acetate anhydrous, edetate disodium, sodium hydroxide, sorbic acid
FDA label
Leading Pharma0.05%

Made by Caplin Steriles

How it looks, what’s in it, NDCs

0.05%

Package NDC
Carton of 5 mL 69315-329-05

Inactive ingredients: sodium acetate, edetate disodium, water, polysorbate 80, sodium hydroxide, glycerin, castor oil, boric acid, sorbic acid
FDA label
Mylan Pharmaceuticals0.05%

How it looks, what’s in it, NDCs

0.05%

Package NDC
Carton of 5 mL 0378-7518-35

Inactive ingredients: boric acid, castor oil, glycerin, polysorbate 80, water, sodium acetate anhydrous, sodium hydroxide, edetate disodium, sorbic acid
FDA label
Upsher-Smith Laboratories0.05%

Product page on upsher-smith.com

How it looks, what’s in it, NDCs

0.05%

Package NDC
Carton of 5 mL 0832-6054-05

Inactive ingredients: castor oil, edetate disodium, glycerin, polysorbate 80, sodium acetate, sodium hydroxide, water, sorbic acid, boric acid
FDA label

Package	NDC
Carton of 5 mL	69238-1380-3

Package	NDC
Carton of 5 mL	65145-161-01

Package	NDC
Carton of 5 mL	43598-588-11

Package	NDC
Carton of 5 mL	69315-329-05

Package	NDC
Carton of 5 mL	0378-7518-35

Package	NDC
Carton of 5 mL	0832-6054-05

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

What the FDA label says

DUREZOL® is a corticosteroid indicated for:

The treatment of inflammation and pain associated with ocular surgery.
The treatment of endogenous anterior uveitis.

Source: the FDA label for Durezol (Sandoz Inc), August 18, 2026. Full label on DailyMed

Good to know

It may look different from Durezol (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Cash prices can differ a lot from one pharmacy to the next, so it can pay to ask two. With insurance, what you pay depends on your plan.
If your pharmacy doesn’t stock it, they can often order it within a day or two.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/durezol/