EC-Naprosyn vs. its authorized generic and generics

How many

How to pay the least

Lowest to pick up today

$57.62 for 30 tablets

Generic naproxen DR 500 mg with the free Team Cuban Card, at pharmacies that take it

Get the free Team Cuban Card. It costs nothing to sign up.See the price and get the card
At a pharmacy that takes it, show the card and ask for generic naproxen DR 500 mg.Find a pharmacy that takes it

By mail, if you can wait a few days $45.47 for 30 tablets delivered ($40.22 plus $5.25 shipping) from Cost Plus Drugs. Make a free account, then have your prescription sent there.

Open Cost Plus Drugs

A regular generic has the same active ingredient as EC-Naprosyn, and the FDA requires it to work the same way.

Compare every option

Brand nameEC-Naprosyn

Authorized genericnaproxen

Regular genericnaproxen

What you’d pay

Not soldNo longer sold

Cash priceAsk the pharmacyUsually among the lowest

Cash price$45.47for 30 tablets at Cost Plus Drugs, with shipping

Same as EC-Naprosyn?

–

Same medicine

Same active ingredientFillers and dyes can differ

Brand nameNot sold

EC-Naprosyn itself isn’t sold as a prescription anymore. Its generic versions, if any, are in the other tabs.

See the authorized generic →

Authorized genericThe NDC to ask for

The same medicine as EC-Naprosyn, without the brand name. Give the pharmacy its NDC to get it.

naproxen

Sold by

Zameer PharmaceuticalsMade for Atnahs Pharma, the company behind EC-Naprosyn

NDC to ask for

500 mgdelayed-release tablet
- 90096-161-0111-digit: 90096-0161-01100 tablets per bottle

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my EC-Naprosyn, can you tell me what I’d pay for the brand, for the authorized generic from Zameer Pharmaceuticals (NDC 90096-161-01), and for a regular generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

EC-Naprosyn itself isn’t sold anymore, so there’s no current brand label to compare. Here’s the authorized generic’s label.

Authorized generic package label from Zameer Pharmaceuticals — Authorized genericZameer Pharmaceuticals

See the ingredients

Active: naproxen 500 mg

Inactive:

Croscarmellose sodium
Magnesium stearate
Methacrylic acid - methyl methacrylate copolymer
Povidone
Sodium hydroxide
Talc
Triethyl citrate

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic naproxen, lowest first.

Pick up in storeDelivered

Pick up in store: Walgreens + Optum Perks $16.22for 60 tablets500 mgFree Optum Perks coupon · not with insuranceFind the nearest store
Delivered: Optum Perks $17.89for 60 tablets500 mgPlus $5 shipping · Not with insurance
Pick up in store: Target (CVS) + Optum Perks $21.71for 60 tablets500 mgFree Optum Perks coupon · not with insuranceFind the nearest store
Delivered: Cost Plus Drugs $40.22for 30 tablets500 mgPlus $5.25 shipping
Delivered: Amazon Pharmacy from $45.50for 30 tablets375 mg $45.50 · 500 mg $120.50Prime members only · $139 a year · Free delivery · Prime price: limits on some medicines if you're over 65 or have Medicare, Medicaid or TRICARE
Pick up in store: Team Cuban Card $57.62for 30 tablets500 mgFree card · Kroger, Albertsons, Safeway, Meijer and many local pharmaciesFind a pharmacy that takes it

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericWho makes it

4 companies sell a generic of EC-Naprosyn that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

ANI PharmaceuticalsDR tablet 375 mg, 500 mg

Made by Novitium Pharma

Product page on anipharmaceuticals.com

How it looks, what’s in it, NDCs

375 mg White to off-white, capsule, 14 mm, marked “N11”

Package NDC
Bottle of 100 70954-925-10

500 mg White to off-white, capsule, 16 mm, marked “N1”

Package NDC
Bottle of 100 70954-928-10

Inactive ingredients: croscarmellose sodium, povidone, silicon dioxide, magnesium stearate, methacrylic acid and ethyl acrylate copolymer, triethyl citrate, talc, water
FDA label
Aurobindo PharmaDR tablet 375 mg, 500 mg

Product page on aurobindousa.com

How it looks, what’s in it, NDCs

375 mg White to off-white, round, 11 mm, marked “N375”

Package NDC
Bottle of 100 59651-986-01
Bottle of 500 59651-986-05

500 mg White to off-white, round, 13 mm, marked “N500”

Package NDC
Bottle of 100 59651-987-01

Inactive ingredients: ferrosoferric oxide, croscarmellose sodium, magnesium stearate, methacrylic acid and ethyl acrylate copolymer, povidone k30, polyethylene glycol 8000, propylene glycol, shellac, dimethicone, sodium hydroxide, talc, titanium dioxide
FDA label
Cameron PharmaceuticalsTablet 375 mg, 500 mg

Made by Nuvo Phamaceuticals

How it looks, what’s in it, NDCs

375 mg White, oval, 14 mm, marked “I1”

Package NDC
Bottle of 100 42494-453-10

500 mg White, oval, 16 mm, marked “I11”

Package NDC
Bottle of 100 42494-454-10

Inactive ingredients: croscarmellose sodium, povidone, silicon dioxide, magnesium stearate, methacrylic acid and ethyl acrylate copolymer, talc, titanium dioxide, triethyl citrate
FDA label
TruPharmaDR tablet 500 mg

Made by TP Anda Holdings

Packages and NDCs

500 mg

Package NDC
Bottle of 100 52817-381-10

Package	NDC
Bottle of 100	70954-925-10

Package	NDC
Bottle of 100	70954-928-10

Package	NDC
Bottle of 100	59651-986-01
Bottle of 500	59651-986-05

Package	NDC
Bottle of 100	59651-987-01

Package	NDC
Bottle of 100	42494-453-10

Package	NDC
Bottle of 100	42494-454-10

Package	NDC
Bottle of 100	52817-381-10

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What it’s used for

What the FDA label says

NAPROXEN Tablets, Naproxen Delayed-Release Tablets, and NAPROXEN SODIUM are indicated for: the relief of the signs and symptoms of: • rheumatoid arthritis • osteoarthritis • ankylosing spondylitis • Polyarticular Juvenile Idiopathic Arthritis NAPROXEN Tablets and NAPROXEN SODIUM are also indicated for: the relief of signs and symptoms of: • tendonitis • bursitis • acute gout the management of: • pain • primary dysmenorrhea

Source: the FDA label for Naproxen (Zameer Pharmaceuticals LLC), August 23, 2025. Full label on DailyMed

Good to know

It may look different from EC-Naprosyn (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Cash prices can differ a lot from one pharmacy to the next, so it can pay to ask two. With insurance, what you pay depends on your plan.
If your pharmacy doesn’t stock it, they can often order it within a day or two.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/ec-naprosyn/