Elfabrio is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How do you pay?

How to pay the least

Given by your care team

Billed by the clinic

Elfabrio is given by a doctor or nurse, not picked up at a pharmacy.

  1. Ask your care team or your plan what you’d pay before your visit.

Compare every option

Question
Brand nameElfabrio
Authorized genericpegunigalsidase alfa
Regular genericpegunigalsidase alfa
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldAsk the pharmacy
Same as Elfabrio?
The original
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–

Brand nameThe maker’s card

Elfabrio Copay Programs (Chiesi Total Care)

Savings card from Chiesi

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a prescription

Sign up on chiesitotalcare.com 

Or call 1-800-784-5840.

In the maker’s words

“You may pay as little as $0 for your Elfabrio prescription.”

From the maker’s offer on chiesitotalcare.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericNot sold

There isn’t one. An authorized generic is Elfabrio itself, from the same company, sold without the brand name, and usually for less. For now Elfabrio is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Elfabrio is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

ELFABRIO is a hydrolytic lysosomal neutral glycosphingolipid-specific enzyme indicated for the treatment of adults with confirmed Fabry disease.

Source: the FDA label for Elfabrio (Chiesi USA, Inc.), July 8, 2024. Full label on DailyMed 

Good to know