Brand-name prescription

Enbrel

etanercept

Compare your options

CompareEnbrelBrand nameAuthorized genericWithout the Enbrel nameRegular genericetanercept
What pharmacies pay$1,042per 0.5 mL syringeNot soldNot sold
Same as Enbrel?The original––
Ways to saveMaker’s cardas little as $0 a dosewith commercial insurance––
With insuranceYour plan’s brand co-pay––

No authorized generic: There isn’t one.

No regular generic: Enbrel is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

Prices are the average U.S. drugstores pay (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

The maker’s savings card

Rx Maker’s savings card Amgen

ENBREL Co-Pay Card (Amgen SupportPlus)

With commercial insurance

as little as $0 a dose

No insurance

This card needs commercial insurance. The maker doesn’t list a cash price on this page.

Get it on enbrel.com

In the maker’s words

“Pay as little as $0 out-of-pocket for each dose…”

From the maker’s offer on enbrel.com, checked September 25, 2026. What you pay depends on your plan. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Before you use a discount card

Discount cards like GoodRx take money off the pharmacy’s cash price. For a brand-name drug, that price is often still high. With commercial insurance, Enbrel’s own card may bring it to as little as $0 a dose.

Look up the discount-card price, then compare it with this estimate. You can use a maker’s card or a discount card, but usually not both on the same fill.

What pharmacies pay

The average U.S. drugstores pay for each strength (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

StrengthEnbrel
25 mg/0.5 mL syringeper 0.5 mL syringe$1,042
50 mg/mL syringeper 1 mL syringe$2,081

Good to know