Brand-name prescription

Enhertu

fam-trastuzumab deruxtecan-nxki

Compare your options

Enhertu is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

Compare	EnhertuBrand name	Authorized genericWithout the Enhertu name	Regular genericfam-trastuzumab deruxtecan-nxki
What pharmacies pay	Price not listed	Not sold	Not sold
Same as Enhertu?	The original	–	–
Ways to save	Maker’s cardas little as $0 a yearwith commercial insurance	–	–
With insurance	Your plan’s brand co-pay	–	–

No authorized generic: There isn’t one.

No regular generic: Enhertu is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

The maker’s savings card

Rx Maker’s savings card Daiichi Sankyo

ENHERTU Patient Savings Program (ENHERTU4U)

With commercial insurance

as little as $0 a year

No insurance

This card needs commercial insurance. The maker doesn’t list a cash price on this page.

Get it on enhertu4u.com

In the maker’s words

“Eligible patients may pay as little as $0 per year for ENHERTU out-of-pocket costs.”

From the maker’s offer on enhertu4u.com, checked September 24, 2026. What you pay depends on your plan. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Good to know

There’s no authorized generic of Enhertu.
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to the clinic’s billing office.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.