How do you pay?

How to pay the least

From

$12.23 for 30 tablets delivered ($6.98 plus $5.25 shipping)

Generic sacubitril and valsartan from Cost Plus Drugs, by mail. Pick the strength on your label above for its own price.

  1. Make a free account on costplusdrugs.com. Ask your prescriber to send the prescription there, or Cost Plus Drugs can transfer it.Open Cost Plus Drugs 
  2. Order generic sacubitril and valsartan. It comes by mail.

Need it today? From $16.40 for 30 tablets with the free Team Cuban Card, at pharmacies that take it. Get the free card and show it there.

See the price and get the card 

With a membership From $9.50 for 30 tablets from Amazon Pharmacy, by mail ($139 a year).

Open Amazon Pharmacy 

A regular generic has the same active ingredient as Entresto, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameEntresto
Authorized genericsacubitril and valsartan
Regular genericsacubitril and valsartan
What you’d pay
At least$340for 30 tablets; pharmacies pay this
Not soldThere isn’t one
From$12.23for 30 tablets at Cost Plus Drugs, with shipping
Same as Entresto?
The original
–
Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from Entresto’s maker. Ask the pharmacy for Entresto’s cash price. With insurance, ask what your plan charges.

Authorized genericNot sold

There isn’t one. An authorized generic is Entresto itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.

See the regular generic →

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic sacubitril and valsartan, lowest first.

Pick up in storeDelivered

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericWho makes it

14 companies sell a generic of Entresto that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • Alembic Pharmaceuticals24 mg / 26 mg, 49 mg / 51 mg, 97 mg / 103 mg
    How it looks, what’s in it, NDCs

    24 mg / 26 mg White to off white, capsule, 9 mm, marked “725 / L”

    PackageNDC
    Bottle of 6062332-556-60
    Bottle of 18062332-556-45
    Carton of 100062332-556-10
    Bottle of 100062332-556-91

    49 mg / 51 mg Light yellow to yellow, capsule, 12 mm, marked “726 / L”

    PackageNDC
    Bottle of 6062332-557-60
    Bottle of 18062332-557-45
    Carton of 100062332-557-10
    Bottle of 100062332-557-91

    97 mg / 103 mg Light pink to pink, capsule, 15 mm, marked “L727”

    PackageNDC
    Bottle of 6062332-558-60
    Bottle of 18062332-558-45
    Carton of 100062332-558-10
    Bottle of 100062332-558-91

    Inactive ingredients: hypromellose, microcrystalline cellulose, crospovidone, silicon dioxide, talc, magnesium stearate, titanium dioxide, polyethylene glycol 4000, ferric oxide red, ferrosoferric oxide, ferric oxide yellow

    FDA label

  • Amneal Pharmaceuticals24 mg / 26 mg, 49 mg / 51 mg, 97 mg / 103 mg

    Made by Crystal Pharmaceutical Suzhou

    How it looks, what’s in it, NDCs

    24 mg / 26 mg Violet-white, oval, 9 mm, marked “SAV / 001”

    PackageNDC
    Bottle of 6069238-2731-1
    Bottle of 18069238-2731-2

    49 mg / 51 mg Pale yellow, oval, 15 mm, marked “SAV / 002”

    PackageNDC
    Bottle of 6069238-2732-1
    Bottle of 18069238-2732-2

    97 mg / 103 mg Pink to light pink, oval, 17 mm, marked “SAV / 003”

    PackageNDC
    Bottle of 6069238-2733-1
    Bottle of 18069238-2733-2

    Inactive ingredients: microcrystalline cellulose, hydroxypropylcellulose, crospovidone, magnesium stearate, talc, silicon dioxide, hypromelloses, titanium dioxide, polyethylene glycol, ferric oxide red, ferrosoferric oxide, ferric oxide yellow

    FDA label

  • ANI Pharmaceuticals24 mg / 26 mg, 49 mg / 51 mg, 97 mg / 103 mg

    Made by Laurus Labs

    Product page on anipharmaceuticals.com

    How it looks, what’s in it, NDCs

    24 mg / 26 mg Violet white, oval, 9 mm, marked “N975”

    PackageNDC
    Bottle of 6070954-975-20
    Bottle of 18070954-975-30
    Bottle of 100070954-975-50

    49 mg / 51 mg Pale yellow, oval, 13 mm, marked “N976”

    PackageNDC
    Bottle of 6070954-976-20
    Bottle of 18070954-976-30
    Bottle of 100070954-976-50

    97 mg / 103 mg Light pink, oval, 15 mm, marked “N977”

    PackageNDC
    Bottle of 6070954-977-20
    Bottle of 18070954-977-30
    Bottle of 100070954-977-50

    Inactive ingredients: crospovidone, hydroxypropyl cellulose, low substituted, magnesium stearate, cellulose, microcrystalline, silicon dioxide, hypromellose 2910 (6 mpa.s), titanium dioxide, polyethylene glycol 4000, talc, ferric oxide red, ferrosoferric oxide, ferric oxide yellow

    FDA label

  • Ascend Laboratories24 mg / 26 mg, 49 mg / 51 mg, 97 mg / 103 mg

    Made by Alkem Laboratories

    How it looks, what’s in it, NDCs

    24 mg / 26 mg Off white to light pink, oval, 10 mm, marked “SV5”

    PackageNDC
    Bottle of 6067877-707-60
    Bottle of 18067877-707-51

    49 mg / 51 mg Pale yellow to yellow, oval, 13 mm, marked “SV1”

    PackageNDC
    Bottle of 6067877-708-60
    Bottle of 18067877-708-51

    49 mg / 51 mg White to off white, oval, 13 mm, marked “SV1”

    PackageNDC
    Carton of 1067877-949-33
    Bottle of 6067877-949-60
    Bottle of 18067877-949-51

    97 mg / 103 mg Light pink to pink, oval, 15 mm, marked “SV2”

    PackageNDC
    Bottle of 6067877-709-60
    Bottle of 18067877-709-51

    97 mg / 103 mg White to off white, oval, 15 mm, marked “SV2”

    PackageNDC
    Carton of 1067877-950-33
    Bottle of 6067877-950-60
    Bottle of 18067877-950-51

    Inactive ingredients: cellulose, microcrystalline, hydroxypropyl cellulose, low substituted, sodium starch glycolate type a potato, silicon dioxide, talc, magnesium stearate, hypromelloses, titanium dioxide, polyethylene glycol 4000, ferric oxide yellow, ferric oxide red, ferrosoferric oxide

    FDA label

  • Biocon Pharma24 mg / 26 mg, 49 mg / 51 mg, 97 mg / 103 mg
    How it looks, what’s in it, NDCs

    24 mg / 26 mg Violet white, oval, 9 mm, marked “SV50 / B”

    PackageNDC
    Bottle of 3070377-031-11
    Bottle of 6070377-031-12
    Bottle of 18070377-031-13
    Bottle of 50070377-031-14

    49 mg / 51 mg Pale yellow, oval, 12 mm, marked “SV100 / B”

    PackageNDC
    Bottle of 3070377-032-11
    Bottle of 6070377-032-12
    Bottle of 18070377-032-13
    Bottle of 50070377-032-14

    97 mg / 103 mg Light pink, oval, 15 mm, marked “SV200 / B”

    PackageNDC
    Bottle of 3070377-033-11
    Bottle of 6070377-033-12
    Bottle of 18070377-033-13
    Bottle of 50070377-033-14

    Inactive ingredients: silicon dioxide, crospovidone (35 .mu.m), hydroxypropyl cellulose, low substituted, magnesium stearate, cellulose, microcrystalline, talc, glyceryl monocaprylocaprate, polyvinyl alcohol, sodium lauryl sulfate, titanium dioxide, ferrosoferric oxide, ferric oxide red, ferric oxide yellow

  • Camber Pharmaceuticals24 mg / 26 mg, 49 mg / 51 mg, 97 mg / 103 mg

    Has a dye: FD&C Blue No. 2 · Made by Hetero Labs

    Product page on camberpharma.com

    How it looks, what’s in it, NDCs

    24 mg / 26 mg White, oval, 7 mm, marked “H / S24”

    PackageNDC
    Bottle of 6031722-673-60
    Bottle of 18031722-673-18

    49 mg / 51 mg Blue, oval, 12 mm, marked “H / S25”

    PackageNDC
    Bottle of 6031722-674-60
    Bottle of 18031722-674-18

    97 mg / 103 mg Brown, oval, 15 mm, marked “H / S26”

    PackageNDC
    Bottle of 6031722-675-60
    Bottle of 18031722-675-18

    Inactive ingredients: crospovidone (120 .mu.m), magnesium stearate, povidone k30, silicon dioxide, diacetylated monoglycerides, titanium dioxide, low-substituted hydroxypropyl cellulose (11% hydroxypropyl; 130000 mw), hypromellose 2910 (15 mpa.s), hypromellose 2910 (5 mpa.s), microcrystalline cellulose 112, FD&C Blue No. 2, ferric oxide red

    FDA label

  • Dr. Reddy’s Laboratories24 mg / 26 mg, 49 mg / 51 mg, 97 mg / 103 mg
    How it looks, what’s in it, NDCs

    24 mg / 26 mg White to off white, oval, 11 mm, marked “50”

    PackageNDC
    Bottle of 6043598-643-60
    Bottle of 18043598-643-18

    49 mg / 51 mg White to off white, oval, 14 mm, marked “100”

    PackageNDC
    Bottle of 6043598-644-60
    Bottle of 18043598-644-18

    97 mg / 103 mg White to off white, oval, 17 mm, marked “200”

    PackageNDC
    Bottle of 6043598-645-60
    Bottle of 18043598-645-18

    Inactive ingredients: calcium carbonate, crospovidone, magnesium stearate, microcrystalline cellulose 102, polysorbate 80, silicon dioxide, diacetylated monoglycerides, hypromellose, shellac, ferrosoferric oxide, propylene glycol, ammonia

    FDA label

  • Lupin Pharmaceuticals24 mg / 26 mg, 49 mg / 51 mg, 97 mg / 103 mg

    Being phased out; sold until December 2028

    How it looks, what’s in it, NDCs

    24 mg / 26 mg White to off-white, oval, 8 mm, marked “C50”

    PackageNDC
    Bottle of 6070748-195-07

    49 mg / 51 mg White to off-white, oval, 12 mm, marked “C100”

    PackageNDC
    Bottle of 6070748-196-07

    97 mg / 103 mg White to off-white, oval, 15 mm, marked “C200”

    PackageNDC
    Bottle of 6070748-197-07

    Inactive ingredients: cellulose, microcrystalline, silicon dioxide, hydroxypropyl cellulose, low substituted, mannitol, magnesium stearate, talc, hypromellose 2910 (3 mpa.s), hypromellose 2910 (15 mpa.s), titanium dioxide, polyethylene glycol 4000, polyethylene glycol 3350, crospovidone

    FDA label

  • Macleods Pharmaceuticals24 mg / 26 mg, 49 mg / 51 mg, 97 mg / 103 mg
    How it looks, what’s in it, NDCs

    24 mg / 26 mg White to off white, oval, 10 mm, marked “J13”

    PackageNDC
    Bottle of 6033342-570-09
    Bottle of 18033342-570-57

    49 mg / 51 mg Light pink, oval, 15 mm, marked “J14”

    PackageNDC
    Bottle of 6033342-571-09
    Bottle of 18033342-571-57

    97 mg / 103 mg White to off white, oval, 17 mm, marked “J15”

    PackageNDC
    Bottle of 6033342-572-09
    Bottle of 18033342-572-57

    Inactive ingredients: cellulose, microcrystalline, hydroxypropyl cellulose, low substituted, silicon dioxide, magnesium stearate, crospovidone, titanium dioxide, talc, polyethylene glycol, polyvinyl alcohol, ferric oxide red, ferric oxide yellow

    FDA label

  • NorthStar Rx24 mg / 26 mg, 49 mg / 51 mg, 97 mg / 103 mg

    Made by Macleods Pharmaceuticals

    Product page on northstarrxllc.com

    How it looks, what’s in it, NDCs

    24 mg / 26 mg White to off white, oval, 10 mm, marked “J13”

    PackageNDC
    Bottle of 6072603-880-01
    Bottle of 18072603-880-02

    49 mg / 51 mg Light pink, oval, 15 mm, marked “J14”

    PackageNDC
    Bottle of 6072603-881-01
    Bottle of 18072603-881-02

    97 mg / 103 mg White to off white, oval, 17 mm, marked “J15”

    PackageNDC
    Bottle of 6072603-882-01
    Bottle of 18072603-882-02

    Inactive ingredients: cellulose, microcrystalline, hydroxypropyl cellulose, low substituted, silicon dioxide, magnesium stearate, crospovidone, titanium dioxide, talc, polyethylene glycol 3350, polyvinyl alcohol, ferric oxide red, polyethylene glycol 4000, ferric oxide yellow

    FDA label

  • Novadoz Pharmaceuticals24 mg / 26 mg, 49 mg / 51 mg, 97 mg / 103 mg

    Made by MSN Laboratories

    Product page on novadozpharma.com

    How it looks, what’s in it, NDCs

    24 mg / 26 mg Purple, oval, 10 mm, marked “M / S1”

    PackageNDC
    Bottle of 6072205-280-60
    Bottle of 18072205-280-18

    49 mg / 51 mg Light Yellow, oval, 13 mm, marked “M / S2”

    PackageNDC
    Bottle of 6072205-281-60
    Bottle of 18072205-281-18

    97 mg / 103 mg Light Pink, oval, 15 mm, marked “M / S3”

    PackageNDC
    Bottle of 6072205-282-60
    Bottle of 18072205-282-18

    Inactive ingredients: microcrystalline cellulose 112, crospovidone (120 .mu.m), croscarmellose sodium, silicon dioxide, talc, magnesium stearate, hypromellose 2910 (6 mpa.s), titanium dioxide, polyethylene glycol 4000, ferric oxide red, ferrosoferric oxide, ferric oxide yellow

    FDA label

  • Novugen Pharma24 mg / 26 mg, 49 mg / 51 mg, 97 mg / 103 mg
    How it looks, what’s in it, NDCs

    24 mg / 26 mg White, oval, 13 mm, marked “N3”

    PackageNDC
    Bottle of 6082293-027-10
    Bottle of 18082293-027-20
    Box of 100082293-027-30

    49 mg / 51 mg Yellow, oval, 13 mm, marked “N2”

    PackageNDC
    Bottle of 6082293-028-10
    Bottle of 18082293-028-20
    Box of 100082293-028-30

    97 mg / 103 mg Pink, oval, 15 mm, marked “N1”

    PackageNDC
    Bottle of 6082293-029-10
    Bottle of 18082293-029-20
    Box of 100082293-029-30

    Inactive ingredients: silicon dioxide, crospovidone, hydroxypropyl cellulose, low substituted, magnesium stearate, microcrystalline cellulose, talc, glyceryl mono- and dicaprylocaprate, polyvinyl alcohol, sodium lauryl sulfate, titanium dioxide, ferric oxide yellow, ferrosoferric oxide, ferric oxide red

    FDA label

  • Torrent Pharmaceuticals24 mg / 26 mg, 49 mg / 51 mg, 97 mg / 103 mg
    How it looks, what’s in it, NDCs

    24 mg / 26 mg VIOLET WHITE, round, 6 mm, marked “U4”

    PackageNDC
    Bottle of 6013668-634-60
    Bottle of 18013668-634-33
    Bottle of 50013668-634-05
    Carton of 100013668-634-74

    49 mg / 51 mg (pale yellow), oval, 11 mm, marked “U5”

    PackageNDC
    Bottle of 6013668-635-60
    Bottle of 18013668-635-33
    Bottle of 50013668-635-05
    Carton of 100013668-635-74

    49 mg / 51 mg White to off white, oval, 11 mm, marked “U5”

    PackageNDC
    Bottle of 6013668-746-60
    Bottle of 18013668-746-33
    Bottle of 50013668-746-05
    Carton of 100013668-746-74

    97 mg / 103 mg Light pink, oval, 15 mm, marked “U7”

    PackageNDC
    Bottle of 6013668-636-60
    Bottle of 18013668-636-33
    Bottle of 50013668-636-05
    Carton of 100013668-636-74

    97 mg / 103 mg White to off white, oval, 15 mm, marked “U7”

    PackageNDC
    Bottle of 6013668-747-60
    Bottle of 18013668-747-33
    Bottle of 50013668-747-05
    Carton of 100013668-747-74

    Inactive ingredients: crospovidone, low-substituted hydroxypropyl cellulose (11% hydroxypropyl; 130000 mw), magnesium stearate, microcrystalline cellulose 112, povidone k30, silicon dioxide, talc, hypromellose 2910 (6 mpa.s), ferrosoferric oxide, polyethylene glycol 4000, titanium dioxide, ferric oxide red, ferric oxide yellow

    FDA label

  • Zydus Lifesciences24 mg / 26 mg, 49 mg / 51 mg, 97 mg / 103 mg

    Has dyes: FD&C Blue No. 2--aluminum lake, FD&C Red No. 40, FD&C Yellow No. 5

    How it looks, what’s in it, NDCs

    24 mg / 26 mg Off-white, oval, 10 mm, marked “71”

    PackageNDC
    Bottle of 6070710-1272-6
    Carton of 10070710-1272-4
    Bottle of 18070710-1272-8

    49 mg / 51 mg Dark-brown, oval, 13 mm, marked “72”

    PackageNDC
    Bottle of 6070710-1273-6
    Carton of 10070710-1273-4
    Bottle of 18070710-1273-8

    97 mg / 103 mg Light orange to orange, oval, 15 mm, marked “73”

    PackageNDC
    Bottle of 6070710-1274-6
    Carton of 10070710-1274-4
    Bottle of 18070710-1274-8

    Inactive ingredients: crospovidone (15 mpa.s at 5%), hydroxypropyl cellulose, low substituted, hypromellose 2910 (6 mpa.s), microcrystalline cellulose 101, microcrystalline cellulose 102, polyethylene glycol 8000, silicon dioxide, sodium stearyl fumarate, titanium dioxide, ferric oxide red, ferric oxide yellow, ferrosoferric oxide, aluminum oxide, FD&C Blue No. 2--aluminum lake, FD&C Red No. 40, FD&C Yellow No. 5

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What to say at the pharmacy

“Before you fill my Entresto, can you tell me what I’d pay for the brand and for a generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

What it’s used for

What the FDA label says

ENTRESTO is a combination of sacubitril, a neprilisin inhibitor, and valsartan, an angiotensin II receptor blocker, and is indicated:

  • to reduce the risk of cardiovascular death and hospitalization for heart failure in adult patients with chronic heart failure. Benefits are most clearly evident in patients with left ventricular ejection fraction (LVEF) below normal.
  • for the treatment of symptomatic heart failure with systemic left ventricular systolic dysfunction in pediatric patients aged one year and older. ENTRESTO reduces NT-proBNP and is expected to improve cardiovascular outcomes.

Source: the FDA label for Entresto (Novartis Pharmaceuticals Corporation), July 6, 2026. Full label on DailyMed 

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