Epclusa vs. its authorized generic and generics

How to pay the least

Ask for the cash price

Authorized generic

Epclusa itself, without the brand name. It usually costs less than Epclusa.

Ask your pharmacy for the cash price of Epclusa’s authorized generic. Its NDC is on this page; the pharmacy may need to order it.See its NDC
Ask for Epclusa’s cash price too, and pick the lower one.

Free from the maker, if you qualify Support Path Patient Assistance Program. Or call 1-855-769-7284.

See if you qualify

None is sold. The authorized generic is the only generic.

Compare every option

Brand nameEpclusa

Authorized genericvelpatasvir and sofosbuvir

Regular genericvelpatasvir and sofosbuvir

What you’d pay

At least$25,940for 30 tablets; pharmacies pay this

Cash priceAsk the pharmacyUsually the lowest

Not soldNone sold

Same as Epclusa?

The original

Same medicine

–

Brand nameThe maker’s card

Epclusa’s maker has a savings card that lowers what you pay at the pharmacy.

Gilead Support Path Co-pay Savings Program

Savings card from Gilead Sciences

No insuranceNeeds insuranceNo cash price listed.

Insurance · as little as $5 a fill

In the maker’s words

“Eligible patients could pay as little as $5…”

From the maker’s offer on epclusa.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericThe NDC to ask for

The same medicine as Epclusa, without the brand name. Give the pharmacy its NDC to get it.

velpatasvir and sofosbuvir

Sold by

Asegua Therapeutics

NDC to ask for

100 mg / 400 mgtablet
- 72626-2701-111-digit: 72626-2701-012 blister packs of 14 tablets

Source: FDA, updated October 30, 2026

What to say at the pharmacy

“Before you fill my Epclusa, can you tell me what I’d pay for the brand, for the authorized generic from Asegua Therapeutics (NDC 72626-2701-1)?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

Brand and authorized generic labels

Official labels and ingredient lists from DailyMed (U.S. National Library of Medicine).

Same active and inactive ingredients as Epclusa.

Authorized generic package label from Asegua Therapeutics — Authorized genericAsegua Therapeutics

See the ingredients

Active: velpatasvir 100 mg · sofosbuvir 400 mg

Inactive, on both labels:

Alcohol
Copovidone k25-31
Croscarmellose sodium
Ferric oxide red
Magnesium stearate
Microcrystalline cellulose
Polyethylene glycol 3350
Polyvinyl alcohol
Talc
Titanium dioxide
Water

Regular genericNot sold

None is sold. The authorized generic is the only generic. Generics usually come once the brand’s patents and exclusivity end. Until then, the authorized generic is the lower-cost way to get Epclusa.

See the authorized generic →

What it’s used for

Chronic hepatitis C

What the FDA label says

EPCLUSA is a fixed-dose combination of sofosbuvir, a hepatitis C virus (HCV) nucleotide analog NS5B polymerase inhibitor, and velpatasvir, an HCV NS5A inhibitor, and is indicated for the treatment of adults and pediatric patients 3 years of age and older with chronic HCV genotype 1, 2, 3, 4, 5, or 6 infection:

without cirrhosis or with compensated cirrhosis
with decompensated cirrhosis for use in combination with ribavirin.

Source: the FDA label for Epclusa (Gilead Sciences, Inc.), June 5, 2024. Full label on DailyMed

Good to know

It may look different from Epclusa (color, shape, or markings). That’s normal for an authorized generic.
If your prescription says “dispense as written,” the pharmacy needs your prescriber’s OK to give you the authorized generic.
Cash prices can differ a lot from one pharmacy to the next, so it can pay to ask two. With insurance, what you pay depends on your plan.
If your pharmacy doesn’t stock it, they can often order it within a day or two.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/epclusa/