How do you pay?

How to pay the least

Ask for the cash price

Epioxa Cross-Linking

We didn’t find one.

  1. Ask your pharmacy for Epioxa Cross-Linking’s cash price, and one or two other pharmacies too.
  2. Epioxa Cross-Linking’s savings card works only with insurance from a job or one you bought.

Compare every option

Question
Brand nameEpioxa Cross-Linking
Authorized genericriboflavin 5-phosphate
Regular genericriboflavin 5-phosphate
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldNone found
Same as the brand?
The original
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–

Brand nameThe maker’s card

EpioxaCareConnect Copay Assistance Program

Savings card from Glaukos

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 per procedure

Sign up on epioxa.com 

Or call 1-844-493-3457.

In the maker’s words

“You may pay as little as $0 for Epioxa treatment…”

From the maker’s offer on epioxa.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Epioxa Cross-Linking itself, from the same company, sold without the brand name, and usually for less. For now Epioxa Cross-Linking is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

We didn’t find one. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

EPIOXA HD and EPIOXA are photoenhancers indicated for use in epithelium-on corneal collagen cross-linking for the treatment of keratoconus in adults and pediatric patients aged 13 years and older, in conjunction with the O2n System and the Boost Goggles.

Source: the FDA label for Epioxa Cross-Linking (Glaukos Corporation), November 18, 2025. Full label on DailyMed 

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