An authorized generic of Epivir-HBV was sold before, but it isn’t sold now. Ask your pharmacist whether a regular generic (lamivudine) is available.
Source: FDA, updated October 30, 2026
How to pay the least
Lowest without a membership
$300.39 for 30 tablets delivered ($295.14 plus $5.25 shipping)
Generic lamivudine 100 mg from Cost Plus Drugs, by mail
- Make a free account on costplusdrugs.com. Ask your prescriber to send the prescription there, or Cost Plus Drugs can transfer it.Open Cost Plus Drugs
- Order generic lamivudine 100 mg. It comes by mail.
With a membership $218.99 for 30 tablets at Costco ($65 a year).
See Costco’s price listA regular generic has the same active ingredient as Epivir-HBV, and the FDA requires it to work the same way.
Compare every option
Question
Brand nameEpivir-HBV
Authorized genericlamivudine
Regular genericlamivudine
What you’d pay
Not soldNo longer sold
Not soldNo longer sold
Cash price$300.39for 30 tablets at Cost Plus Drugs, with shippingWith a membership: $218.99 at Costco
Same as Epivir-HBV?
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Same active ingredientFillers and dyes can differ
Details for each option
Details for
Brand nameNot sold
Epivir-HBV itself isn’t sold as a prescription anymore. Its generic versions, if any, are in the other tabs.
Authorized genericNot sold now
Regular genericWhere to buy it
Pharmacies’ own cash prices for generic lamivudine, lowest first.
Pick up in storeDelivered
- Pick up in store: Costco $218.99for 30 tablets100 mgMembers only · $65 a yearFind the nearest store
- Delivered: Costco $218.99for 30 tablets100 mgMembers only · $65 a year · Plus shipping
- Delivered: Cost Plus Drugs $295.14for 30 tablets100 mgPlus $5.25 shipping
- Pick up in store: Sam's Club See its pricePlus members only · $120 a yearFind the nearest store
From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.
About these prices
Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.
Regular genericWho makes it
One company sells a generic of Epivir-HBV that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.
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Apotex100 mg
Has lactose
How it looks, what’s in it, NDCs
100 mg Orange-brown, oval, 12 mm, marked “APO / LMV100”
Package NDC Bottle of 60 60505-3250-6 Inactive ingredients: anhydrous lactose, crospovidone (120 .mu.m), silicon dioxide, magnesium stearate, hypromellose 2910 (5 mpa.s), hydroxypropyl cellulose (1600000 wamw), polyethylene glycol 8000, titanium dioxide, ferric oxide red, ferric oxide yellow
Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.
What it’s used for
What the FDA label says
EPIVIR-HBV is indicated for the treatment of chronic hepatitis B virus (HBV) infection associated with evidence of hepatitis B viral replication and active liver inflammation. The following points should be considered when initiating therapy with EPIVIR-HBV:
- Due to high rates of resistance development in treated patients, initiation of treatment with EPIVIR-HBV should only be considered when the use of an alternative antiviral agent with a higher genetic barrier to resistance is not available or appropriate.
- EPIVIR-HBV has not been evaluated in patients co-infected with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis delta virus.
- EPIVIR-HBV has not been evaluated in liver transplant recipients or in patients with chronic hepatitis B virus infection with decompensated liver disease.
Source: the FDA label for Epivir-HBV (Glaxosmithkline), December 22, 2021. Full label from the FDA (PDF)
Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/epivir-hbv/