Brand-name prescription

Esbriet

pirfenidone

Compare your options

Compare	EsbrietBrand name	Authorized genericWithout the Esbriet name	Regular genericpirfenidone
What pharmacies pay	Price not listed	Not sold	from$0.69–1.96per tablet
Same as Esbriet?	The original	–	Same active ingredientFillers and dyes can differ
Ways to save	Maker’s cardas little as $5 a monthwith commercial insurance	–	Ask for it by name
With insurance	Brand co-pay, usually the highest	–	Usually the lowest co-pay

No authorized generic: There isn’t one.

Prices are the average U.S. drugstores pay (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

The maker’s savings card

Rx Maker’s savings card Legacy Pharma Inc. SEZC

Esbriet Co-pay Program

With commercial insurance

as little as $5 a month

No insurance

This card needs commercial insurance. The maker doesn’t list a cash price on this page.

The card pays up to $25,000 a year.

Get it on esbriet.com

In the maker’s words

“insurance could pay as little as $5…”

From the maker’s offer on esbriet.com, checked September 25, 2026. What you pay depends on your plan. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Before you use a discount card

Discount cards like GoodRx take money off the pharmacy’s cash price. For a brand-name drug, that price is often still high. With commercial insurance, Esbriet’s own card may bring it to as little as $5 a month.

Look up the discount-card price, then compare it with this estimate. You can use a maker’s card or a discount card, but usually not both on the same fill.

What pharmacies pay

The average U.S. drugstores pay for each strength (source: Medicaid, September 23, 2026). What you pay depends on your plan or the pharmacy.

Strength	Regular generic
267 mg tabletper tablet	$0.69
801 mg tabletper tablet	$1.96

Good to know

A regular generic has the same active ingredient, strength and form as Esbriet, and the FDA requires it to work the same way. Its fillers and dyes can differ, so it may look different.
There’s no authorized generic of Esbriet.
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.