EstroGel vs. generic estradiol: side by side

How to pay the least

Ask for the cash price

Generic estradiol

No pharmacy we check posts a price for it.

Ask your pharmacy for the cash price of generic estradiol.Find pharmacies near you
Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

A regular generic has the same active ingredient as EstroGel, and the FDA requires it to work the same way.

Compare every option

Brand nameEstroGel

Authorized genericestradiol

Regular genericestradiol

What you’d pay

Cash priceAsk the pharmacyUsually the highest price

Not soldThere isn’t one

Cash priceAsk the pharmacyUsually the lowest

Same as EstroGel?

The original

–

Same active ingredientFillers and dyes can differ

Brand nameNo maker’s card

We didn’t find a savings card or cash price from EstroGel’s maker. Ask the pharmacy for EstroGel’s cash price. With insurance, ask what your plan charges.

Authorized genericNot sold

There isn’t one. An authorized generic is EstroGel itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.

See the regular generic →

Regular genericWho makes it

2 companies sell a generic of EstroGel that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

ANI Pharmaceuticals0.75 mg/1.25 g

Made by Novitium Pharma

Product page on anipharmaceuticals.com

How it looks, what’s in it, NDCs

0.75 mg/1.25 g

Package NDC
Bottle of 50 g 70954-646-10

Inactive ingredients: water, alcohol, trolamine, carbomer homopolymer type b
FDA label
Solaris Pharma0.75 mg/1.25 g

Product page on solaris-pharma.com

Packages and NDCs

0.75 mg/1.25 g

Package NDC
Carton of 50 g 73473-308-50

FDA label

Package	NDC
Bottle of 50 g	70954-646-10

Package	NDC
Carton of 50 g	73473-308-50

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What to say at the pharmacy

“Before you fill my EstroGel, can you tell me what I’d pay for the brand and for a generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

What it’s used for

What the FDA label says

EstroGel 0.06% is an estrogen indicated for:

Treatment of moderate to severe vasomotor symptoms due to menopause
Treatment of moderate to severe symptoms of vulvar and vaginal atrophy due to menopause

Source: the FDA label for EstroGel (ASCEND Therapeutics US, LLC), May 29, 2026. Full label on DailyMed

Good to know

A regular generic may look different from EstroGel. The FDA requires it to work the same way.
We didn’t find a savings card from EstroGel’s maker.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/estrogel/