How do you pay?

How to pay the least

Ask for the cash price

Hepcludex

Hepcludex is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

  1. Ask your pharmacy for Hepcludex’s cash price, and one or two other pharmacies too.
  2. Hepcludex’s savings card works only with insurance from a job or one you bought.

Free from the maker, if you qualify Support Path Patient Assistance Program. Or call 1-855-769-7284.

See if you qualify 

Compare every option

Question
Brand nameHepcludex
Authorized genericbulevirtide
Regular genericbulevirtide
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldAsk the pharmacy
Same as Hepcludex?
The original
–
–

Brand nameThe maker’s card

Hepcludex Co-pay Savings Program (Gilead Support Path)

Savings card from Gilead Sciences

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a fill

Sign up on hepcludex.com 

Or call 1-855-769-7284.

In the maker’s words

“You may pay as low as a $0 co-pay with the HEPCLUDEX Co-pay Savings Program…”

From the maker’s offer on hepcludex.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Hepcludex itself, from the same company, sold without the brand name, and usually for less. For now Hepcludex is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Hepcludex is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

HEPCLUDEX is a sodium taurocholate co-transporting polypeptide (NTCP)-directed HDV attachment inhibitor indicated for the treatment of chronic HDV infection in adults without cirrhosis or with compensated cirrhosis. This indication is approved under accelerated approval based on participants who achieved a decrease in HDV RNA and alanine aminotransferase (ALT) normalization. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial(s).

Source: the FDA label for Hepcludex (Gilead Sciences, Inc.), May 22, 2026. Full label on DailyMed 

Good to know