Hepzato is given by a doctor or nurse and billed by the clinic, not a pharmacy. Your care team and your insurance decide which product you get, so ask them what you’d pay.

How do you pay?

How to pay the least

Given by your care team

Billed by the clinic

Hepzato is given by a doctor or nurse, not picked up at a pharmacy.

  1. Ask your care team or your plan what you’d pay before your visit.

Compare every option

Question
Brand nameHepzato
Authorized genericmelphalan
Regular genericmelphalan
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldNone found
Same as Hepzato?
The original
–
–

Brand nameThe maker’s card

HEPZATO KIT Access 360 Copay Assistance Program

Savings card from Delcath Systems

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $0 a treatment

The card takes up to $10,000 a year off your co-pay.

Sign up on hepzatokitaccess.com 

In the maker’s words

“Eligible individuals can receive the Hepzato Kit™ for as little as $0…”

From the maker’s offer on hepzatokitaccess.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Authorized genericNot sold

There isn’t one. An authorized generic is Hepzato itself, from the same company, sold without the brand name, and usually for less. For now Hepzato is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

We didn’t find one. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

HEPZATO is an alkylating drug indicated as a liver-directed treatment for adult patients with uveal melanoma with unresectable hepatic metastases affecting less than 50% of the liver and no extrahepatic disease, or extrahepatic disease limited to the bone, lymph nodes, subcutaneous tissues, or lung that is amenable to resection or radiation.

Source: the FDA label for Hepzato (Delcath Systems, Inc.), June 9, 2026. Full label on DailyMed 

Good to know