Herceptin Hylecta savings card: as little as $0 a treatment with commercial insurance

How to pay the least

Ask for the cash price

Herceptin Hylecta

This medicine is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

Ask your pharmacy for Herceptin Hylecta’s cash price, and one or two other pharmacies too.
Herceptin Hylecta’s savings card works only with insurance from a job or one you bought.

Free from the maker, if you qualify Genentech Patient Foundation. Do not have insurance coverage for their Genentech medicine and their household makes less than $150,000 per year Or call (888) 941-3331.

See if you qualify

Compare every option

Brand nameHerceptin Hylecta

Authorized generictrastuzumab and hyaluronidase-oysk

Regular generictrastuzumab and hyaluronidase-oysk

What you’d pay

Cash priceAsk the pharmacy

Not soldThere isn’t one

Not soldAsk the pharmacy

Same as the brand?

The original

–

Brand nameThe maker’s card

Genentech Oncology Co-pay Assistance Program

Savings card from Genentech

No insuranceNeeds insuranceNo cash price listed.

Insurance · as little as $0 a treatment

The card takes up to $25,000 a year off your co-pay.

Or call 1-888-249-4918.

In the maker’s words

“With the Genentech Oncology Co-pay Assistance Program, eligible patients with commercial insurance could pay as little as $0 per treatment for Herceptin HYLECTA.”

From the maker’s offer on herceptinhylecta.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Herceptin Hylecta itself, from the same company, sold without the brand name, and usually for less. For now Herceptin Hylecta is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

This medicine is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

HER2-positive breast cancer

What the FDA label says

HERCEPTIN HYLECTA is a combination of trastuzumab, a HER2/neu receptor antagonist, and hyaluronidase, an endoglycosidase, indicated in adults for:

The treatment of HER2-overexpressing breast cancer.

Select patients for therapy based on an FDA-authorized companion diagnostic for trastuzumab.

Source: the FDA label for Herceptin Hylecta (Genentech, Inc.), September 22, 2026. Full label on DailyMed

Good to know

“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.

Prices checked November 2, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/herceptin-hylecta/