Free from the maker, if you qualify Lilly Cares Foundation Patient Assistance Program. Note: These income limits are 300% (Group 1 Medications), 400% (Group 2 Medications), and 500% (Group 3 & 4 Medications) of 2026 Federal Poverty Guidelines. Or call 1-800-545-6962.
Humalog Mix50/50 is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.
Compare every option
Question
Brand nameHumalog Mix50/50
Authorized genericinsulin lispro
Regular genericinsulin lispro
What you’d pay
Cash price$35a month with the maker’s card
Not soldThere isn’t one
Not soldNone sold yet
Same as Humalog Mix50/50?
The original
–
–
Coverage: With Medicare, a month’s supply of a covered insulin costs no more than $35.
Details for each option
Details for
Brand nameThe maker’s card
Lilly Insulin Value Program
Savings card from Eli Lilly
No insurance$35a month
Insurance · as little as$35a month
The card takes up to $3,000 a month off your co-pay.
“You must have commercial drug insurance that covers your Covered Insulin and a prescription for an approved use consistent with FDA-approved product labeling to pay as little as $35 for a 1-month prescription fill of your Covered Insulin.”
“Through the Lilly Insulin Value Program, all Lilly insulins are available for $35 a month whether you have commercial insurance or no insurance.”
From the maker’s offer on insulins.lilly.com, checked October 27, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Maker’s card or discount card?
A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s price above. You can usually use one or the other on a fill, not both.
Authorized genericNot sold
There isn’t one. An authorized generic is Humalog Mix50/50 itself, from the same company, sold without the brand name, and usually for less. For now Humalog Mix50/50 is the only choice; its maker’s savings card can lower what you pay.
Humalog Mix50/50 is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.
HUMALOG® Mix50/50™ is a mixture of insulin lispro protamine, an intermediate-acting human insulin analog, and insulin lispro, a rapid-acting human insulin analog, indicated to improve glycemic control in adults with diabetes mellitus.
Limitations of Use:
The proportions of rapid-acting and intermediate-acting insulins are fixed and do not allow for basal versus prandial dose adjustments.
Source: the FDA label for Humalog Mix50/50 (Eli Lilly and Company), July 27, 2026. Full label on DailyMed
Good to know
“Commercial insurance” means a plan from a job, from the marketplace, or one you buy yourself. A retiree plan that’s part of Medicare counts as Medicare. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.
Most cards need a sign-up on the maker’s site, and many work only if your plan covers the drug. Then give the card’s details to your pharmacy.
Don’t stop or change a medicine without talking to your pharmacist or prescriber.
Prices checked October 27, 2026. Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/humalog-mix50-50/