How do you pay?

How to pay the least

Lowest posted price

$35 a month

Humalog Mix75/25 from Eli Lilly, without insurance.

  1. Sign up for Lilly Insulin Value Program. Or call 1-866-923-1953.Sign up on insulins.lilly.com 

Free from the maker, if you qualify Lilly Cares Foundation Patient Assistance Program. Note: These income limits are 300% (Group 1 Medications), 400% (Group 2 Medications), and 500% (Group 3 & 4 Medications) of 2026 Federal Poverty Guidelines. Or call 1-800-545-6962.

See if you qualify 

Humalog Mix75/25 is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

Compare every option

Question
Brand nameHumalog Mix75/25
Authorized genericinsulin lispro
Regular genericinsulin lispro
What you’d pay
Cash price$35a month with the maker’s card
Not soldThere isn’t one
Not soldNone sold yet
Same as Humalog Mix75/25?
The original
–
–

Coverage: With Medicare, a month’s supply of a covered insulin costs no more than $35.

Brand nameThe maker’s card

Lilly Insulin Value Program

Savings card from Eli Lilly

No insurance $35 a month
Insurance · as little as $35 a month

The card takes up to $3,000 a month off your co-pay.

Sign up on insulins.lilly.com 

Or call 1-866-923-1953.

In the maker’s words

“You must have commercial drug insurance that covers your Covered Insulin and a prescription for an approved use consistent with FDA-approved product labeling to pay as little as $35 for a 1-month prescription fill of your Covered Insulin.”

“Through the Lilly Insulin Value Program, all Lilly insulins are available for $35 a month whether you have commercial insurance or no insurance.”

From the maker’s offer on insulins.lilly.com, checked October 27, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s price above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Humalog Mix75/25 itself, from the same company, sold without the brand name, and usually for less. For now Humalog Mix75/25 is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Humalog Mix75/25 is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

HUMALOG® Mix75/25™ is a mixture of insulin lispro protamine, an intermediate-acting human insulin analog, and insulin lispro, a rapid-acting human insulin analog indicated to improve glycemic control in adults with diabetes mellitus.

Limitations of Use:

The proportions of rapid-acting and intermediate-acting insulins are fixed and do not allow for basal versus prandial dose adjustments.

Source: the FDA label for Humalog Mix75/25 (Eli Lilly and Company), June 16, 2026. Full label on DailyMed 

Good to know