Hyperrho Mini-Dose

Generic name: rho(D) immune globulin (human)

Used for: Preventing Rh antibodies after an early miscarriage or abortion (first 12 weeks)

How do you pay?

How to pay the least

Ask for the cash price

Hyperrho Mini-Dose

This medicine is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold.

  1. Ask your pharmacy for Hyperrho Mini-Dose’s cash price, and one or two other pharmacies too.

Compare every option

Question
Brand nameHyperrho Mini-Dose
Authorized genericrho(D) immune globulin (human)
Regular genericrho(D) immune globulin (human)
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Not soldAsk the pharmacy
Same as the brand?
The original
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Brand nameNo maker’s card

We didn’t find a savings card or cash price from Hyperrho Mini-Dose’s maker. Ask the pharmacy for Hyperrho Mini-Dose’s cash price. With insurance, ask what your plan charges.

Authorized genericNot sold

There isn’t one. An authorized generic is Hyperrho Mini-Dose itself, from the same company, sold without the brand name, and usually for less. For now Hyperrho Mini-Dose is the only choice; ask the pharmacy for its cash price, or your plan what it charges.

Regular genericNot sold

This medicine is a biologic. Biologics don’t have generics, but some have biosimilars or an unbranded version from the same maker. Ask your pharmacist or prescriber whether one is sold. Generics usually come once the brand’s patents and exclusivity end. Until then, ask the pharmacy for Hyperrho Mini-Dose’s cash price, or your plan what it charges.

What it’s used for

What the FDA label says

HyperRHO Mini-Dose is recommended to prevent the isoimmunization of Rho(D) negative women at the time of spontaneous or induced abortion of up to 12 weeks’ gestation provided the following criteria are met:

  • The mother must be Rho(D) negative and must not already be sensitized to the Rho(D) antigen.
  • The father is not known to be Rho(D) negative.
  • Gestation is not more than 12 weeks at termination.

Note: Rho(D) Immune Globulin (Human) prophylaxis is not indicated if the fetus or father can be determined to be Rh negative. If the Rh status of the fetus is unknown, the fetus must be assumed to be Rho(D) positive, and HyperRHO Mini-Dose should be administered to the mother.

FOR ABORTIONS OR MISCARRIAGES OCCURRING AFTER 12 WEEKS’ GESTATION, A STANDARD DOSE OF Rho(D) IMMUNE GLOBULIN (HUMAN) IS INDICATED.

HyperRHO Mini-Dose should be administered within 3 hours or as soon as possible after spontaneous passage or surgical removal of the products of conception. However, if HyperRHO Mini-Dose is not given within this time period, consideration should still be given to its administration since clinical studies in male volunteers have demonstrated the effectiveness of Rho(D) Immune Globulin (Human) in preventing isoimmunization as long as 72 hours after infusion of Rho(D) positive red cells.

Source: the FDA label for Hyperrho Mini-Dose (GRIFOLS USA, LLC), June 24, 2025. Full label on DailyMed 

Good to know

Prices change: confirm with the pharmacy before you fill. drugalt.com/drug/hyperrho-mini-dose/