How do you pay?

How to pay the least

Ask for the cash price

Generic sitagliptin and metformin XR

Only Amazon Pharmacy posts a price for sitagliptin and metformin XR, 30 tablets, and it’s for members.

  1. Ask your pharmacy for the cash price of generic sitagliptin and metformin XR.Find pharmacies near you 
  2. Ask one or two other pharmacies too. Cash prices for the same generic can differ a lot from store to store.

With a membership From $132.50 for 30 tablets from Amazon Pharmacy, by mail ($139 a year).

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A regular generic has the same active ingredient as Janumet XR, and the FDA requires it to work the same way.

Compare every option

Question
Brand nameJanumet XR
Authorized genericsitagliptin and metformin
Regular genericsitagliptin and metformin
What you’d pay
At least$310for 30 tablets; pharmacies pay this
Not soldThere isn’t one
Cash priceMembers only$132.50 for 30 tablets at Amazon Pharmacy
Same as Janumet XR?
The original
–
Same active ingredientFillers and dyes can differ

Brand nameThe maker’s card

Merck Cash-Pay Gateway

Savings card from Merck

Janumet XR’s maker has a savings program. Its page doesn’t list a dollar amount.

Sign up on merckcashpaygateway.com 

From the maker’s site, checked November 2, 2026. Check the maker’s page for who can use it.

Brand nameTrumpRx.gov price

TrumpRx.gov, the federal government’s drug price site, lists Janumet XR at a price its maker agreed to, for people paying without insurance.

From TrumpRx.gov, read October 28, 2026. Its page opens on this price; other strengths and amounts are priced there too. With insurance, check your co-pay first: it may be lower.

Authorized genericNot sold

There isn’t one. An authorized generic is Janumet XR itself, from the same company, sold without the brand name, and usually for less. A regular generic is sold, with the same active ingredient: ask the pharmacy for its price.

See the regular generic →

Regular genericWhere to buy it

Pharmacies’ own cash prices for generic sitagliptin and metformin, lowest first.

Delivered

From each pharmacy’s own site, read November 2, 2026. Confirm the price before you fill.

About these prices

Prices change, can differ by store and state, and may depend on the strength and how many you take. With insurance, ask what your plan charges; it can be less.

Regular genericWho makes it

One company sells a generic of Janumet XR that the FDA rates a substitute. A pharmacy fills whichever one it stocks. To get a certain maker, ask for it by name; most pharmacies can order it in a day or two.

  • Par HealthAll 3 strengths

    Has a dye: FD&C Blue No. 2 · Made by PH Health

    How it looks, what’s in it, NDCs

    50 mg / 1,000 mg Light green, oval, 22 mm, marked “A318”

    PackageNDC
    Bottle of 6010370-318-02

    50 mg / 500 mg Light blue, oval, 21 mm, marked “A317”

    PackageNDC
    Bottle of 6010370-317-02

    100 mg / 1,000 mg Blue, oval, 22 mm, marked “A351”

    PackageNDC
    Bottle of 3010370-351-11

    Inactive ingredients: silicon dioxide, hypromellose 2208 (100000 mpa.s), hypromellose 2910 (6 mpa.s), kaolin, polyethylene glycol 3350, povidone k30, propyl gallate, sodium stearyl fumarate, hydroxypropyl cellulose, FD&C Blue No. 2, titanium dioxide, carnauba wax, ferric oxide yellow, microcrystalline cellulose 102

    FDA label

Who sells it: FDA and Medicaid records, updated weekly. Each maker’s page, card and program is from its own site.

What to say at the pharmacy

“Before you fill my Janumet XR, can you tell me what I’d pay for the brand and for a generic?”

Paying cash? Ask for each one’s cash price. With insurance, ask what your plan charges for each.

What it’s used for

What the FDA label says

JANUMET XR is a combination of sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, and metformin hydrochloride (HCl), a biguanide indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Limitations of Use:

  • Not for the treatment of type 1 diabetes.
  • Has not been studied in patients with a history of pancreatitis.

Source: the FDA label for Janumet XR (Merck Sharp & Dohme LLC), August 11, 2026. Full label on DailyMed 

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