How do you pay?

How to pay the least

Ask for the cash price

Jylamvo

Sold only in a different form, strength or formula. Switching to one would need a new prescription, so ask your prescriber whether it could work for you.

  1. Ask your pharmacy for Jylamvo’s cash price, and one or two other pharmacies too.
  2. Jylamvo’s savings card works only with insurance from a job or one you bought.

Compare every option

Question
Brand nameJylamvo
Authorized genericmethotrexate
Regular genericmethotrexate
What you’d pay
Cash priceAsk the pharmacy
Not soldThere isn’t one
Other forms onlyAsk your doctor
Same as Jylamvo?
The original
–
–

Brand nameThe maker’s card

JYLAMVO Savings Program

Savings card from Shorla Oncology

No insuranceNeeds insuranceNo cash price listed.
Insurance · as little as $5 a month

The card takes up to $230 a month off your co-pay.

Sign up on shorlaoncology.com 

In the maker’s words

“If you have commercial drug insurance that covers JYLAMVO®, you can get a 30-day supply for as little as $5.00.”

From the maker’s offer on shorlaoncology.com, checked November 2, 2026. Co-pay cards can’t be used with Medicare (including Medicare Advantage), Medicaid, TRICARE or VA.

Maker’s card or discount card?

A discount card like GoodRx lowers the pharmacy’s cash price, but for a brand-name drug that price often stays high. Compare it with the maker’s card above. You can usually use one or the other on a fill, not both.

Authorized genericNot sold

There isn’t one. An authorized generic is Jylamvo itself, from the same company, sold without the brand name, and usually for less. For now Jylamvo is the only choice; its maker’s savings card can lower what you pay.

See the brand name →

Regular genericNot sold

Sold only in a different form, strength or formula. Switching to one would need a new prescription, so ask your prescriber whether it could work for you. Generics usually come once the brand’s patents and exclusivity end. Until then, the maker’s savings card is the way to pay less.

See the brand name →

What it’s used for

What the FDA label says

JYLAMVO is a folate analog metabolic inhibitor indicated for the:

  • Treatment of adults and pediatric patients with acute lymphoblastic leukemia (ALL) as part of a combination chemotherapy maintenance regimen
  • Treatment of adults with mycosis fungoides
  • Treatment of adults with relapsed or refractory non-Hodgkin lymphoma as part of a metronomic combination regimen
  • Treatment of adults with rheumatoid arthritis
  • Treatment of pediatric patients with polyarticular juvenile idiopathic arthritis (pJIA)
  • Treatment of adults with severe psoriasis

Source: the FDA label for Jylamvo (SHORLA ONCOLOGY INC.), June 8, 2026. Full label on DailyMed 

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